Martin J. Lohse

Max Delbrück Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

100h-index37.3kcitations541works2.42yr avg
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Research Topics

Receptor Mechanisms and Signaling(292), Neuropeptides and Animal Physiology(89), Neuroscience and Neuropharmacology Research(65), Protein Kinase Regulation and GTPase Signaling(49), Adenosine and Purinergic Signaling(47)

Publications540 total

MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor
Nature Communications·2025· 3 citedOpen Access
Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
GPR3 ligands discovered through combined virtual and conformational biosensor-based screening
2025Open Access
Pharmacological characterization of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4
Molecular Pharmacology·2025· 2 citedOpen Access
Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms
2024· 1 citedOpen Access
Cell swelling enhances ligand-driven β-adrenergic signaling
Nature Communications·2024· 2 citedOpen Access
Nanobody against SARS-CoV-2 non-structural protein Nsp9 inhibits viral replication in human airway epithelia
Molecular Therapy — Nucleic Acids·2024· 4 citedOpen Access
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions
PLoS Biology·2024· 8 citedOpen Access
MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor
2024· 4 citedOpen Access
ADAM19 cleaves the PTH receptor and associates with brachydactyly type E
Life Science Alliance·2024· 1 citedOpen Access
Unraveling fast G-protein coupled receptor mobility and binding
Biophysical Journal·2024
Nanobodies against SARS-CoV-2 non-structural protein Nsp9 inhibit viral replication by targeting innate immunity
2023· 1 citedOpen Access
G Protein–Coupled Receptor Signaling: New Insights Define Cellular Nanodomains
The Annual Review of Pharmacology and Toxicology·2023· 44 citedOpen Access
Abstract P391: Cellular Camp Nanoarchtecture-signaling Changes Cause Hypertension With Brachydactyly
Hypertension·2023
Cell swelling enhances canonical β-adrenergic signaling
2023Open Access
Abstract 010: Phosphodiesterase 3a Catalytic-domain Mutants Cause Hypertension With Brachydactyly
Hypertension·2022
Functional modulation of PTH1R activation and signaling by RAMP2
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
Functional modulation of PTH1R activation and signaling by RAMP2
Proceedings of the National Academy of Sciences·2022· 25 citedOpen Access
Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB<sub>1</sub>R) “Cis-On” Agonist
ACS Chemical Neuroscience·2022· 18 citedOpen Access
Fluorescence spectroscopy of low-level endogenous β-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes
2022· 1 citedOpen Access
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Frequent Co-authors

Viacheslav O. Nikolaev(10), Moritz Bünemann(7), Davide Calebiro(6), Carsten Hoffmann(6), Marc G. Caron(5), Robert J. Lefkowitz(5), Stefan Engelhardt(5), Lutz Hein(5), Kristina Lorenz(5), Karl‐Norbert Klotz(4), Graeme Milligan(4), Susanne Pippig(4), Lakshmi A. Devi(3), Jean‐Philippe Pin(3), Jean‐Pierre Vilardaga(3), Ulrike Zabel(3), S Andexinger(3), Roland Jahns(3), Valérie Boivin(3), Mechthild Puzicha(3)