Eric Zhu

Washington University in St. Louis — United States

Immunology and Microbiology · Life Sciences

6h-index863citations22works1.52yr avg
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Research Topics

Immunotherapy and Immune Responses(11), Immune Cell Function and Interaction(7), Cancer Immunotherapy and Biomarkers(5), Monoclonal and Polyclonal Antibodies Research(5), CAR-T cell therapy research(5)

Publications22 total

Preclinical Safety of APG777, A Novel Extended Half-Life Anti-Interleukin-13 Monoclonal Antibody, in Cynomolgus Monkeys
International Journal of Toxicology·2025· 1 citedOpen Access
In vitro potency and pharmacokinetics of APG777, a novel anti–IL-13 mAb
Journal of Allergy and Clinical Immunology Global·2025· 2 citedOpen Access
Do the benefits of IDH mutations in high-grade glioma persist beyond the first recurrence? A multi-institutional retrospective analysis
Journal of Neuro-Oncology·2025· 2 citedOpen Access
The impact of sociodemographic background on clinical presentation of high-grade gliomas: a multi-institutional retrospective analysis
Journal of Neuro-Oncology·2025Open Access
APG777, a Humanized IgG1 Monoclonal Antibody, Binds to IL-13 with High Affinity and Potently Blocks IL-13 Signaling in Multiple in vitro Assays
SKIN The Journal of Cutaneous Medicine·2024· 3 citedOpen Access
APG777, a High-Affinity Humanized IgG1 Monoclonal Antibody Targeting IL-13, Demonstrates Prolonged Half-Life in Non-Human Primates
SKIN The Journal of Cutaneous Medicine·2024· 1 citedOpen Access
EXTH-02. A TERT-SPECIFIC TCR-LIKE ANTIBODY CAR T CELL APPROACH FACILITATES KILLING OF GLIOBLASTOMA
Neuro-Oncology·2023Open Access
Abstract 526: Novel mechanisms of Neuropilin-1 inhibition result in improved tumor growth inhibition <i>in vivo</i>
Cancer Research·2021
683 A novel mechanism of neuropilin-1 inhibition results in improved tumor growth inhibition in vivo
Regular and Young Investigator Award Abstracts·2020· 2 citedOpen Access
Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types
Journal of Molecular Biology·2018· 8 citedOpen Access
Redox Interfaces for Electrochemically Controlled Protein–Surface Interactions: Bioseparations and Heterogeneous Enzyme Catalysis
Chemistry of Materials·2017· 46 cited
Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses
The Journal of Experimental Medicine·2017· 48 citedOpen Access
Abstract A42: Combination immunotherapy of an autochthonous murine lung cancer model expressing human CEA as a tumor-associated self-antigen
Cancer Immunology Research·2017
Temporally Programmed CD8α[superscrip +] DC Activation Enhances Combination Cancer Immunotherapy
Elsevier eBooks·2016
Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy
Cell Reports·2016· 43 citedOpen Access
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
Nature Medicine·2016· 527 citedOpen Access
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
DSpace@MIT (Massachusetts Institute of Technology)·2016Open Access
Synergistic anti-tumor immune response to combination immunotherapy consisting of anti-tumor antibodies, extended half-life Interleukin-2, and other immunomodulatory agents
DSpace@MIT (Massachusetts Institute of Technology)·2016Open Access
Abstract B120: Characterization and combination immunotherapy treatment of an inducible autochthonous murine lung cancer model expressing human carcinoembryonic antigen (CEA) as a tumor-associated self-antigen
Cancer Immunology Research·2016
Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2
Cancer Cell·2015· 179 citedOpen Access
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Frequent Co-authors

K. Dane Wittrup(9), Monique J. Kauke(8), Kelly D. Moynihan(7), Cary F. Opel(7), Naveen K. Mehta(7), Darrell J. Irvine(7), Gregory L. Szeto(5), Alice Tzeng(5), Kavya Rakhra(4), Ryan L. Kelly(4), Byron H. Kwan(4), Carl Dambkowski(4), Wuhbet Abraham(3), Jennifer R. Cochran(3), Hussam Shaheen(3), Jason Oh(3), Tanner M. Johanns(3), J Engreitz(2), Christina Williamson(2), Michael H. Zhang(2)