Cary F. Opel

Gilead Sciences (United States) — United States

Immunology and Microbiology · Life Sciences

9h-index1.4kcitations18works0.02yr avg
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Research Topics

Immunotherapy and Immune Responses(9), CAR-T cell therapy research(7), Immune Cell Function and Interaction(6), Monoclonal and Polyclonal Antibodies Research(5), Cancer Immunotherapy and Biomarkers(4)

Publications18 total

Accurate definition of control strategies using cross validated stepwise regression and Monte Carlo simulation
Journal of Biotechnology·2019· 9 citedOpen Access
Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types
Journal of Molecular Biology·2018· 8 citedOpen Access
More accurate process understanding from process characterization studies using Monte Carlo simulation, regularized regression, and classification models
2018
Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors
Journal of Clinical Investigation·2017· 329 citedOpen Access
Abstract A52: Eradication of large established tumors with combination immunotherapy engaging innate and adaptive immunity
Cancer Immunology Research·2017
Temporally Programmed CD8α[superscrip +] DC Activation Enhances Combination Cancer Immunotherapy
Elsevier eBooks·2016
Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy
Cell Reports·2016· 43 citedOpen Access
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
Nature Medicine·2016· 527 citedOpen Access
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
DSpace@MIT (Massachusetts Institute of Technology)·2016Open Access
Abstract B120: Characterization and combination immunotherapy treatment of an inducible autochthonous murine lung cancer model expressing human carcinoembryonic antigen (CEA) as a tumor-associated self-antigen
Cancer Immunology Research·2016
Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2
Cancer Cell·2015· 179 citedOpen Access
Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution
Proceedings of the National Academy of Sciences·2015· 118 citedOpen Access
T cell mediated combination immunotherapy
DSpace@MIT (Massachusetts Institute of Technology)·2015Open Access
A graphene-based physiometer array for the analysis of single biological cells
Scientific Reports·2014· 41 citedOpen Access
Combined treatment using adoptive cell therapy, extended pharmacokinetic IL-2, and tumor-specific antibodies leads to cures of established B16F10 tumors and extended in vivo T cell survival
Journal for ImmunoTherapy of Cancer·2013Open Access
Emergent Properties of Nanosensor Arrays: Applications for Monitoring IgG Affinity Distributions, Weakly Affined Hypermannosylation, and Colony Selection for Biomanufacturing
ACS Nano·2013· 54 cited
Quantitative modeling of viable cell density, cell size, intracellular conductivity, and membrane capacitance in batch and fed‐batch CHO processes using dielectric spectroscopy
Biotechnology Progress·2010· 110 cited
Cyclical articular joint loading leads to cartilage thinning and osteopontin production in a novel in vivo rabbit model of repetitive finger flexion
Osteoarthritis and Cartilage·2005· 17 cited

Frequent Co-authors

K. Dane Wittrup(13), Kelly D. Moynihan(7), Eric Zhu(7), Monique J. Kauke(7), Alice Tzeng(6), Naveen K. Mehta(6), Darrell J. Irvine(6), Gregory L. Szeto(5), Ryan L. Kelly(5), Byron H. Kwan(5), Kavya Rakhra(4), J Engreitz(3), Adrienne M. Rothschilds(3), Sudha Kumari(3), Wuhbet Abraham(3), Kevin Hu(3), Heikyung Suh(3), Douglas A. Lauffenburger(3), Christina Williamson(2), Michael H. Zhang(2)