Rik G.H. Lindeboom

Wellcome Sanger Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index4.8kcitations81works13.02yr avg
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Research Topics

Single-cell and spatial transcriptomics(15), SARS-CoV-2 and COVID-19 Research(12), Hippo pathway signaling and YAP/TAZ(11), COVID-19 Clinical Research Studies(10), Genomics and Chromatin Dynamics(10)

Publications81 total

Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferation
Proceedings of the National Academy of Sciences·2025Open Access
Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection
Nature Communications·2025Open Access
Temporal Dynamics of Antigen-Specific T Cell Expansion in Primary SARS-CoV-2 Infection
2025Open Access
MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation
2025· 2 citedOpen Access
Temporal multi-omics analysis of COVID-19 in end-stage kidney disease
Cell Genomics·2025· 2 citedOpen Access
SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections
Nature Communications·2024· 10 citedOpen Access
Early human lung immune cell development and its role in epithelial cell fate
2024
Human SARS-CoV-2 challenge uncovers differences in local and systemic cellular responses associated with protection from infection and distinct infection states
2024
Author Correction: Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
Nature·2024· 2 citedOpen Access
Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq
Nature Protocols·2024· 3 citedOpen Access
Multi-modal generative modeling for joint analysis of single-cell T cell receptor and gene expression data
Nature Communications·2024· 19 citedOpen Access
Temporal multi-omic analysis of COVID-19 in end-stage kidney disease
2024Open Access
Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
Nature·2024· 103 citedOpen Access
Author Correction: Age-specific nasal epithelial responses to SARS-CoV-2 infection
Nature Microbiology·2024· 1 citedOpen Access
Early Human Lung Immune Cell Development and Its Role in Epithelial Cell Fate
2024
Age-specific nasal epithelial responses to SARS-CoV-2 infection
Nature Microbiology·2024· 43 citedOpen Access
Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers
Nature·2024· 1 citedOpen Access
Decoding chromatin states by proteomic profiling of nucleosome readers
Nature·2024· 61 citedOpen Access
mvTCR - trained models
Zenodo (CERN European Organization for Nuclear Research)·2024Open Access
Early human lung immune cell development and its role in epithelial cell fate
Science Immunology·2023· 85 citedOpen Access
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Frequent Co-authors

Michiel Vermeulen(24), Sarah A. Teichmann(23), Kerstin B. Meyer(15), Muzlifah Haniffa(15), Krzysztof Polański(14), Marko Nikolić(14), Kaylee B. Worlock(13), Masahiro Yoshida(13), Menna R. Clatworthy(12), Elena Prigmore(10), Lira Mamanova(10), Lisa M. Dratva(10), Ni Huang(9), Josephine L. Barnes(9), Sam M. Janes(9), Marijke Baltissen(9), Anna Wilbrey-Clark(9), Zewen Kelvin Tuong(8), Claire M. Smith(8), Pascal W.T.C. Jansen(8)