Kristen M. Varney

University of Maryland, Baltimore — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.1kcitations92works1.82yr avg
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Research Topics

S100 Proteins and Annexins(38), Computational Drug Discovery Methods(13), Heat shock proteins research(12), Clostridium difficile and Clostridium perfringens research(11), Toxin Mechanisms and Immunotoxins(8)

Publications92 total

1HN, 13C, and 15N resonance assignments of Ca2+-calmodulin bound to a BP2 peptide derived from the sheep STRA6 vitamin A transporter (residues 625–656)
Biomolecular NMR Assignments·2025Open Access
Decoding Allostery: How Interactions Lock S100B Conformations and What K55A Mutation Teaches Us
Journal of Chemical Information and Modeling·2025
Hierarchical AF2RAVE for Multiconformation Virtual Screening Targeting S100 Ca<sup>2+</sup>-Binding Proteins
Journal of Chemical Theory and Computation·2025· 2 cited
Pore formation by the CDTb component of the Clostridioides difficile binary toxin is Ca2+-dependent
Communications Biology·2025· 2 citedOpen Access
Observing nucleotide flipping in DNA using indirect 2′-F nucleotide probes and 19F NMR
Nucleic Acids Research·2025· 4 citedOpen Access
Hierarchical AF2RAVE for multi-conformation virtual screening targeting S100 Ca$^{2+}$-binding proteins
2025Open Access
Sumoylation of thymine DNA glycosylase impairs productive binding to substrate sites in DNA
Journal of Biological Chemistry·2024· 8 citedOpen Access
Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”
Cell Calcium·2024Open Access
Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins
Toxins·2024Open Access
Deuterium spin relaxation of fractionally deuterated ribonuclease H using paired 475 and 950 MHz NMR spectrometers
Journal of Biomolecular NMR·2024· 3 citedOpen Access
Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator
Journal of Chemical Information and Modeling·2024· 2 cited
Deciphering S100B allosteric signaling: The role of TRTK as an ensemble modulator
Biophysical Journal·2024Open Access
Membrane binding and pore formation is Ca <sup>2+</sup> -dependent for the <i>Clostridioides difficile</i> binary toxin
2023Open Access
Characterizing inhibitors of human AP endonuclease 1
PLoS ONE·2023· 16 citedOpen Access
1H, 13C, and 15N assignments of the mRNA binding protein hnRNP A18
Biomolecular NMR Assignments·2022· 3 citedOpen Access
Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery
Journal of Molecular Biology·2022· 8 citedOpen Access
1H, 13C, and 15N assignments of the mRNA binding protein hnRNP A18
Research Square (Research Square)·2022Open Access
Physiologically Relevant Free Ca2+ Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6
Journal of Molecular Biology·2021· 10 citedOpen Access
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23–225)
Biomolecular NMR Assignments·2021· 3 citedOpen Access
Structural Fine‐Tuning of <i>Clostridioides difficile</i> Binary Toxin Components for Therapeutic Applications
The FASEB Journal·2021
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Frequent Co-authors

David J. Weber(33), Paul T. Wilder(18), Edwin Pozharski(11), Alexander D. MacKerell(9), Nathan T. Wright(8), Thomas H. Charpentier(7), Melissa A. Liriano(6), Alexander C. Drohat(6), Eric A. Toth(6), Mary E. Cook(6), Raquel Godoy‐Ruiz(5), Anne R. Bresnick(4), Danna B. Zimmer(4), L.S. Pidugu(4), Wenbo Yu(4), Wuyuan Lu(4), Richard R. Rustandi(4), Andrew Coop(4), Arnaldo Caruso(4), Francesca Caccuri(4)