John R. Walker

Genomics Institute of the Novartis Research Foundation — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

66h-index26.5kcitations167works2.52yr avg
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Research Topics

DNA Repair Mechanisms(15), Tuberculosis Research and Epidemiology(13), Ubiquitin and proteasome pathways(12), Mycobacterium research and diagnosis(11), Malaria Research and Control(9)

Publications167 total

The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
2025Open Access
Triggering AHR resolves TGF-β1 induced fibroblast activation and promotes AT1 cell regeneration in alveolar organoids
Communications Biology·2025· 1 citedOpen Access
Heterogeneity in Effects of Poverty-Alleviating Interventions
AEA Papers and Proceedings·2025
Data and code for Heterogeneity in Effects of Poverty-alleviating Interventions
ICPSR Data Holdings·2025Open Access
617 Combined histone deacetylase and PD-L1 inhibition is safe and efficacious for the treatment of virus-associated cancers: results of a phase II clinical trial
Regular and Young Investigator Award Abstracts·2024Open Access
Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing
2024· 4 citedOpen Access
AHR activation accelerates the resolution of TGF-β1 induced fibroblast activation and promotes alveolar type 1 cell regeneration in alveolar organoids
2024Open Access
The Effects of Mental Health Interventions on Labor Market Outcomes in Low- and Middle-Income Countries
2024· 13 citedOpen Access
CSB and SMARCAL1 compete for RPA32 at stalled forks and differentially control the fate of stalled forks in BRCA2-deficient cells
Nucleic Acids Research·2024· 6 citedOpen Access
The Effects of Mental Health Interventions on Labor Market Outcomes in Low- and Middle-Income Countries
SSRN Electronic Journal·2024· 2 citedOpen Access
The Effects of Mental Health Interventions on Labor Market Outcomes in Low- and Middle-Income Countries
SSRN Electronic Journal·2024· 1 citedOpen Access
CSB Regulates Pathway Choice in Response to DNA Replication Stress Induced by Camptothecin
International Journal of Molecular Sciences·2023· 3 citedOpen Access
A high-throughput cigarette smoke-treated bronchosphere model for disease-relevant phenotypic compound screening
PLoS ONE·2023· 7 citedOpen Access
“3D, human renal proximal tubule (RPTEC-TERT1) organoids ‘tubuloids’ for translatable evaluation of nephrotoxins in high-throughput”
PLoS ONE·2022· 6 citedOpen Access
Role of Cockayne Syndrome Group B Protein in Replication Stress: Implications for Cancer Therapy
International Journal of Molecular Sciences·2022· 7 citedOpen Access
Cockayne syndrome group B protein uses its DNA translocase activity to promote mitotic DNA synthesis
DNA repair·2022· 7 cited
Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells
Nucleic Acids Research·2021· 11 citedOpen Access
The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites
International Journal of Molecular Sciences·2021· 10 citedOpen Access
Hunting FOX: Using Fragments to Sniff Out Drug Leads for Antibiotic Discovery
Bulletin of the American Physical Society·2020
CSB cooperates with SMARCAL1 to maintain telomere stability in ALT cells
Journal of Cell Science·2020· 22 citedOpen Access
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Frequent Co-authors

Peter G. Schultz(11), Sirano Dhe‐Paganon(8), S. Whitney Barnes(7), G.V. Avvakumov(6), Richard Glynne(6), Kelli Kuhen(6), Srinivasa P. S. Rao(5), John B. Hogenesch(5), Sheng Xue(5), Elizabeth A. Winzeler(5), Kévin Pethe(4), Pablo Bifani(4), Bee Huat Tan(4), Anna Dubrovska(4), David Plouffe(4), Arnab K. Chatterjee(4), Thierry T. Diagana(4), Luis R. Camacho(4), Jan Jiřiček(3), Mahesh Nanjundappa(3)