Alice Bakker

Menlo School — United States

Medicine · Health Sciences

4h-index476citations15works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(5), Immune Cell Function and Interaction(5), CAR-T cell therapy research(3), Cancer Immunotherapy and Biomarkers(2), Immunotherapy and Immune Responses(2)

Publications15 total

1097 MDK1654: a branched synthetic peptide that activates both the IL-7 receptor and the βγc form of the IL-2/15 receptor
Regular and Young Investigator Award Abstracts·2022Open Access
709 Peptidyl IL-2/15Rβγc-restricted agonists, highly-attenuated and linked to anti-PD-1 antibodies to achieve selectivity and amplified potency in stimulating PD-1high lymphocytes
Regular and Young Investigator Award Abstracts·2021· 3 citedOpen Access
566 MDK-202: An empirically-designed peptidyl agonist of the IL-2/15βγc receptor, devoid of Rα interaction, unrelated to IL-2 or IL-15, and fused to an Fc-domain for PK enhancement
Regular and Young Investigator Award Abstracts·2020Open Access
691 MDK-271: A dual function molecule consisting of empirically-designed peptidyl agonists of IL-2/15Rβγc and IL-7Rαγc, unrelated to IL-2, IL-15, or IL-7, incorporated into a bispecific Fc fusion protein
Regular and Young Investigator Award Abstracts·2020· 1 citedOpen Access
567 MDK1319/MDK-701: A potent fully efficacious peptidyl agonist of IL-7Rαγc, designed with no reference to cytokine or receptor structure and unrelated to IL-7, fused to an Fc-domain for PK enhancement
Regular and Young Investigator Award Abstracts·2020· 2 citedOpen Access
Abstract PR12: Assessing in vivo mechanisms regulating the therapeutic activity of bi-specific T-cell engager (BiTE®) molecules in immunocompetent mice expressing a chimeric human/mouse CD3ϵ receptor
Cancer Immunology Research·2020
De hybride docent: een grensganger
2019
Abstract 2559: Generation and evaluation of an FLT3 CAR-T cell therapy for the treatment of acute myeloid leukemia
Cancer Research·2018· 2 cited
Novel protein therapeutic joint retention strategy based on collagen‐binding Avimers
Journal of Orthopaedic Research®·2017· 20 citedOpen Access
FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/β-Klotho Bispecific Protein
PLoS ONE·2013· 56 citedOpen Access
Abstract B233: c-Met antagonist Avimer™ polypeptide that exhibits potent <i>in vivo</i> and <i>in vitro</i> inhibitor activity
Molecular Cancer Therapeutics·2009
Erratum: Corrigendum: Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
Nature Biotechnology·2006· 1 citedOpen Access
Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
Nature Biotechnology·2005· 237 cited
Peptides Which Bind to E-selectin and Block Neutrophil Adhesion
Journal of Biological Chemistry·1995· 153 citedOpen Access
Primary immune-response induction by dendritic cells
Data Archiving and Networked Services (DANS)·1995· 1 citedOpen Access

Frequent Co-authors

Steven E. Cwirla(6), William J. Dower(6), Amy Duguay(5), Kevin W. Moore(5), Ronald W. Barrett(5), Prarthana Joshi(5), Praechompoo Pongtornpipat(5), Michael Needels(5), Blake Williams(4), Wayne To(3), Richard W. Smith(3), Erik A. Whitehorn(3), Candace Swimmer(3), Melissa Thomas(3), Sandra Wang(3), Joshua S. Silverman(2), Qiang Lü(2), Ben M Alba(2), Alberto Rivas(2), Hon Le(2)