Johanna D. Stoeckler

Brown University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.6kcitations47works0.02yr avg
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Research Topics

Biochemical and Molecular Research(32), Adenosine and Purinergic Signaling(25), Cytomegalovirus and herpesvirus research(13), HIV/AIDS drug development and treatment(10), Synthesis and Characterization of Heterocyclic Compounds(7)

Publications47 total

Regulation of Interleukin-13 Receptor Constituents on Mature Human B Lymphocytes
Journal of Biological Chemistry·1998· 35 citedOpen Access
Purine Nucleoside Phosphorylase. 3. Reversal of Purine Base Specificity by Site-Directed Mutagenesis
Biochemistry·1997· 78 cited
Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism
Biochemistry·1997· 126 cited
1α,25-Dihydroxyvitamin D3 modulates CD38 expression on human lymphocytes
The Journal of Immunology·1996· 46 citedOpen Access
The synthesis and biological evaluation of 4-p-nitrobenzylthio-v-triazolo [4,5-d]pyridazine and imidazo[4,5-d]pyridazine ribosides as potential nucleoside transport inhibitors
Bioorganic & Medicinal Chemistry·1996· 12 cited
ChemInform Abstract: Nucleic Acid Related Compounds. Part 82. Conversions of Adenosine to Inosine 5′‐Thioether Derivatives with Aspergillus oryzae Adenosine Deaminase or Alkyl Nitrites. Substrate and Inhibitory Activities of Inosine 5′‐Thioether Derivatives with Purine Nucleoside Phosphorylase.
ChemInform·1995
Adenosine Deaminase Inhibitors. Synthesis and Biological Evaluation of Putative Metabolites of (+)-erythro-9-(2S-Hydroxy-3R-nonyl)adenine
Journal of Medicinal Chemistry·1994· 18 citedOpen Access
ChemInform Abstract: Synthesis and Biological Evaluation of N4‐Substituted Imidazo‐ and v‐ Triazolo(4,5‐d)pyridazine Nucleosides.
ChemInform·1994
ChemInform Abstract: Adenosine Deaminase Inhibitors. Synthesis and Biological Evaluation of 4‐Amino‐1‐(2(S)‐hydroxy‐3(R)‐nonyl)‐1H‐imidazo(4,5‐c)pyridine (3‐Deaza‐ (+)‐EHNA) and Certain C1′ Derivatives.
ChemInform·1994
X-Ray Crystallographic and Kinetic Analysis of Human Purine Nucleoside Phosphorylase Complexes with 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carobxamide and 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamidine
Nucleosides and Nucleotides·1994· 6 cited
Nucleic Acid Related Compounds. 82. Conversions of Adenosine to Inosine 5′-Thioether Derivatives with<i>Aspergillus oryzae</i>Adenosine Deaminase or Alkyl Nitrites. Substrate and Inhibitory Activities of Inosine 5′-Thioether Derivatives with Purine Nucleoside Phosphorylase
Nucleosides and Nucleotides·1994· 8 cited
Adenosine deaminase inhibitors. Synthesis and biological evaluation of 4-amino-1-[2(S)-hydroxy-3(R)-nonyl]-1H-imidazo[4,5-c]pyridine [3-deaza-(+)-EHNA] and certain C1' derivatives
Journal of Medicinal Chemistry·1994· 11 citedOpen Access
Synthesis and biological evaluation of N4-substituted imidazo- and v-triazolo[4,5-d]pyridazine nucleosides
Journal of Medicinal Chemistry·1993· 14 citedOpen Access
Adenosine deaminase inhibitors. Synthesis and biological evaluation of C1' and nor-C1' derivatives of (+)-erythro-9-[2(S)-hydroxy-3(R)-nonyl]adenine
Journal of Medicinal Chemistry·1992· 17 citedOpen Access
Inhibition of nucleoside transport by nitrobenzylthioformycin analogs
Biochemical Pharmacology·1990· 8 cited
Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution.
Journal of Biological Chemistry·1990· 178 citedOpen Access
Inhibition of Purine Nucleoside Phosphorylase by Phosphonoalkylpurines 1
Nucleosides Nucleotides & Nucleic Acids·1989· 14 cited
Influx of 5'-deoxy-5'-methylthioadenosine into HL-60 human leukemia cells and erythrocytes.
Journal of Biological Chemistry·1987· 11 citedOpen Access
Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides
Biochemical Pharmacology·1987· 34 cited
Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation.
PubMed·1986· 33 cited
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Frequent Co-authors

Robert E. Parks(31), Elie Abushanab(8), Raymond P. Panzica(8), S.E. Ealick(7), Shih-Fong Chen(5), W.J. Cook(4), Kailash C. Agarwal(4), Gerald W. Crabtree(4), John R. Helliwell(3), Shih‐Hsi Chu(3), Anne F. Poirot(3), Daniel L. Dexter(3), Todd M. Savarese(3), Michel Bessodes(3), Charles E. Bugg(3), Jacqueline C. Bussolari(3), S.A. Rule(2), Trevor J. Greenhough(2), Y.S. Babu(2), J. Habash(2)