Colin Adrain

Queen's University Belfast — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index5.7kcitations86works3.82yr avg
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Research Topics

Cell death mechanisms and regulation(24), Autophagy in Disease and Therapy(11), Ubiquitin and proteasome pathways(11), Cellular transport and secretion(9), Endoplasmic Reticulum Stress and Disease(9)

Publications86 total

Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
Nature Communications·2025· 2 citedOpen Access
Membrane association prevents premature degradation and mitigates inefficient biogenesis of suboptimal membrane proteins
2025Open Access
Functional redundancy in Oxa1-family insertases supports robust membrane insertion of influenza A virus M2 viroporin
2025Open Access
A critical role for the ER Membrane Complex (EMC) in lipid droplet homeostasis
2025Open Access
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
2024· 1 citedOpen Access
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil
Nucleic Acids Research·2024· 11 citedOpen Access
Issue Information
FEBS Journal·2024Open Access
Can the <scp>HB‐EGF</scp>/<scp>EGFR</scp> pathway restore injured neurons?
FEBS Journal·2024· 3 citedOpen Access
Issue Information
FEBS Journal·2024Open Access
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling
Nature Communications·2024· 21 citedOpen Access
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity
Cellular and Molecular Life Sciences·2024· 7 citedOpen Access
Issue Information
FEBS Journal·2024Open Access
Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil
2023· 2 citedOpen Access
Issue Information
FEBS Journal·2023Open Access
Issue Information
FEBS Journal·2023Open Access
Xport-A functions as a chaperone by stabilizing the first five transmembrane domains of rhodopsin-1
iScience·2023Open Access
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity
2023· 1 citedOpen Access
Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis
Molecular Metabolism·2023· 6 citedOpen Access
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth
Life Science Alliance·2023· 15 citedOpen Access
Organelle homeostasis: from cellular mechanisms to disease
FEBS Journal·2022· 15 citedOpen Access
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Frequent Co-authors

Séamus J. Martin(24), Emma Burbridge(9), Matthew Freeman(8), Marina Badenes(8), Kvido Střı́šovský(7), Patrick J. Duriez(6), Emma M. Creagh(6), Pedro Domingos(5), Marius K. Lemberg(4), Sean P. Cullen(4), Miguel Cavadas(4), Ioanna Oikonomidi(4), Abdulbasit Amin(4), Érika de Carvalho(4), Pedro Faísca(4), Elizabeth A. Slee(3), Markus Zettl(3), Rebecca C. Taylor(3), Marion MacFarlane(3), Alexander U. Lüthi(3)