Alexander U. Lüthi

University of Bern — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.8kcitations20works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Cell death mechanisms and regulation(7), Hepatitis C virus research(2), Liver Disease Diagnosis and Treatment(2), Cancer-related Molecular Pathways(2), Autophagy in Disease and Therapy(2)

Publications20 total

Rapid decline of anti‐hepatitis C virus (<scp>HCV</scp>) antibodies following early treatment of incident <scp>HCV</scp> infections in <scp>HIV</scp>‐infected men who have sex with men
HIV Medicine·2018· 18 citedOpen Access
Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery
Cell Death and Disease·2017· 30 citedOpen Access
Hepatitis delta-associated mortality in HIV/HBV-coinfected patients
Journal of Hepatology·2016· 130 cited
Comparison of respiratory and Meningitis/Encephalitis viruses detected by FilmArray® multiplex PCR versus real-time PCR
Journal of Clinical Virology·2016
Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis
Journal of Clinical Virology·2012· 25 cited
Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α
Molecular Cell·2011· 278 citedOpen Access
Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme
Journal of Biological Chemistry·2011· 82 citedOpen Access
Jämförelse av fallhändelsedokumentation före och efter införandet av en kvalitetsnorm för fallprevention
KTH Publication Database DiVA (KTH Royal Institute of Technology)·2011Open Access
The identification and functional characterisation of caspase substrates involved in inflammation
Trinity's Access to Research Output (TARA) (Trinity College Dublin)·2010Open Access
Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases
Immunity·2009· 664 citedOpen Access
Nucleophosmin Is Cleaved and Inactivated by the Cytotoxic Granule Protease Granzyme M during Natural Killer Cell-mediated Killing
Journal of Biological Chemistry·2008· 45 citedOpen Access
Executioner caspase-3 and caspase-7 are functionally distinct proteases
Proceedings of the National Academy of Sciences·2008· 589 citedOpen Access
Analysis of apoptosis in cell-free systems
Methods·2008· 8 cited
Chapter Seventeen Two‐Dimensional Gel‐Based Analysis of the Demolition Phase of Apoptosis
Methods in enzymology on CD-ROM/Methods in enzymology·2008· 6 cited
Human and murine granzyme B exhibit divergent substrate preferences
The Journal of Experimental Medicine·2007· 5 cited
Human and murine granzyme B exhibit divergent substrate preferences
The Journal of Cell Biology·2007· 116 citedOpen Access
The CASBAH: a searchable database of caspase substrates
Cell Death and Differentiation·2007· 420 citedOpen Access
p73 Status in B-cell Chronic Lymphocytic Leukaemia
Leukemia & lymphoma/Leukemia and lymphoma·2004· 28 cited
Human ΔNp73 regulates a dominant negative feedback loop for TAp73 and p53
Cell Death and Differentiation·2001· 334 citedOpen Access
70 Modulation of neuronal properties by extracellular proteolytic activity
International Journal of Developmental Neuroscience·1996

Frequent Co-authors

Séamus J. Martin(11), Sean P. Cullen(8), Patrick J. Duriez(3), Inna S. Afonina(3), Colin Adrain(3), Clare Sheridan(2), Ed C. Lavelle(2), J. Walsh(2), Tobias Grob(2), Urban Novak(2), Barbara Hügli(2), H.U. Graber(2), Martin F. Fey(2), Susan E. Logue(2), Jan Paul Medema(2), Matthias Cavassini(2), Enos Bernasconi(2), Hansjakob Furrer(2), Andri Rauch(2), Gilles Wandeler(2)