Dingjiang Liu

Regeneron (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index2.3kcitations61works2.92yr avg
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Research Topics

Protein purification and stability(23), Monoclonal and Polyclonal Antibodies Research(17), RNA and protein synthesis mechanisms(9), Protein Structure and Dynamics(8), Viral Infectious Diseases and Gene Expression in Insects(7)

Publications61 total

Comprehensive forced degradation study revealing diverse chemical and physical degradation pathways of AAV8
Gene Therapy·2026Open Access
Insights into Photo Degradation and Stabilization Strategies of Antibody–Drug Conjugates with Camptothecin Payloads
Pharmaceutics·2025Open Access
Comprehensive Forced Degradation Study Revealing Diverse Chemical and Physical Degradation Pathways of AAV8
2025Open Access
Recommendation of IV Dose Preparation Practices Using Closed System Transfer Devices (CSTD) for Accurate Dosing
The AAPS Journal·2025
PROPERMAB: an integrative framework for <i>in silico</i> prediction of antibody developability using machine learning
mAbs·2025· 4 citedOpen Access
Prediction of long-term stability of high-concentration formulations to support rapid development of antibodies against SARS-CoV-2
mAbs·2025· 2 citedOpen Access
Injection site reactions of biologics and mitigation strategies
AAPS Open·2025· 7 citedOpen Access
Comparative analysis of empty and full adeno-associated viruses under stress conditions by anion-exchange chromatography, analytical ultracentrifugation, and mass photometry
Journal of Pharmaceutical Sciences·2025· 5 cited
Development of an optimized SEC method for characterization of genome DNA leakage from adeno-associated virus products
Analytical and Bioanalytical Chemistry·2024· 3 cited
PROPERMAB: an integrative framework for <i>in silico</i> prediction of antibody developability using machine learning
2024· 1 citedOpen Access
Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping
Journal of Pharmaceutical and Biomedical Analysis·2024· 10 citedOpen Access
Lyophilization as an effective tool to develop AAV8 gene therapy products for refrigerated storage
International Journal of Pharmaceutics·2023· 9 cited
Characterization of Microbial Growth Potential in Antibody Drug IV Admixtures by Microbial Challenge
Journal of Pharmaceutical Sciences·2023· 2 cited
Genome DNA leakage of Adeno–Associated virus under freeze–thaw stress
International Journal of Pharmaceutics·2022· 30 cited
Deciphering the High Viscosity of a Therapeutic Monoclonal Antibody in High Concentration Formulations by Microdialysis-Hydrogen/Deuterium Exchange Mass Spectrometry
Journal of Pharmaceutical Sciences·2022· 3 cited
Antiviral Monoclonal Antibody Cocktails As a Modern Weapon in Combating Pandemics
Therapeutic Delivery·2021· 12 citedOpen Access
Characterization of Proteinaceous Particles in Monoclonal Antibody Drug Products Using Mass Spectrometry
Journal of Pharmaceutical Sciences·2021· 3 citedOpen Access
Ophthalmic Product Development for Biologics
AAPS advances in the pharmaceutical sciences series·2021· 2 cited
A hydrophobic interaction chromatography method suitable for quantitating individual monoclonal antibodies contained in co-formulated drug products
Journal of Pharmaceutical and Biomedical Analysis·2020· 12 citedOpen Access
Chapter 14: Practical Considerations in High Concentration Formulation Development for Monoclonal Antibody Drug Products
AAPS advances in the pharmaceutical sciences series·2020· 7 cited
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Frequent Co-authors

Mohammed Shameem(14), Daniel F. Wyss(11), David N. Brems(6), Richard L. Remmele(6), Mitsuhiko Ikura(5), Yu‐Sen Wang(5), Da Ren(4), Ramil F. Latypov(4), Shuai Li(4), Melanie J. Cocco(3), Rieko Ishima(3), Stefan Bagby(3), Yoshihiro Nakatani(3), Pavel V. Bondarenko(3), Samuel H. Wilson(3), Timothy S. Harvey(3), Andrei A. Raibekas(3), Bowen Jiang(3), Jennifer J. Gesell(3), Yuan Cao(3)