Rajini Srinivasan

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.9kcitations42works0.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(8), Hereditary Neurological Disorders(8), Signaling Pathways in Disease(7), Genetic Syndromes and Imprinting(6), Nerve injury and regeneration(5)

Publications42 total

Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation
Nature Communications·2025Open Access
Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation
2024Open Access
Supplementary Figures 1-2 from Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate
2023Open Access
Supplementary Figures 1-2 from Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate
2023Open Access
Data from Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate
2023Open Access
Data from Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate
2023Open Access
Constitutive protein degradation induces acute cell death via proteolysis products
2023· 11 citedOpen Access
Targeted degradation via direct 26S proteasome recruitment
Nature Chemical Biology·2022· 100 citedOpen Access
Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide
Stem Cell Reports·2020· 81 citedOpen Access
Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage
Science Advances·2020· 79 citedOpen Access
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
Nature·2019· 292 citedOpen Access
Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals
2018· 3 citedOpen Access
Nicotinamide protects against PVR by preventing RPE cells to undergo EMT
Kölner Universitäts PublikationsServer (Universität zu Köln)·2018Open Access
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells
Circulation Research·2017· 22 citedOpen Access
<i>FOXS1</i> is a Master Regulator of Pathological Epithelial to Mesenchymal Transition in Human Epithelia
2017Open Access
FOXS1 drives EMT in retinal pigment, mammary and hepatic epithelial cells through p38 activation by TGFΒ1 and TNFa
Investigative Ophthalmology & Visual Science·2016Open Access
Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest
Cell·2015· 389 citedOpen Access
Abstract 97: Epigenetic Signatures Contribute to the Superior Endothelial Cell Identity in Human Induced Pluripotent Stem Cells Derived From Endothelial Cells
Circulation Research·2015
Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2
Journal of Neuroscience·2015· 56 citedOpen Access
Differential Sox10 genomic occupancy in myelinating glia
Glia·2015· 100 cited
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Frequent Co-authors

John Svaren(27), Joanna Wysocka(10), R. Matthew Ward(7), Erin A. Jones(6), Sung‐Wook Jang(6), Vivian Fu(6), Joseph R. Dobosy(6), Joshua A. Desotelle(6), Nima Almassi(6), Richard Weindruch(6), David F. Jarrard(6), Gennifer M. Mager(5), Guannan Sun(5), Sündüz Keleş(5), Courtney Krueger(5), Jonathan A. Ewald(5), Mark E. Berres(5), Tomek Swigut(4), M Snyder(4), Camila Lopez‐Anido(4)