Joel D. A. Tyndall

University of Otago — New Zealand

Medicine · Health Sciences

43h-index7.5kcitations169works3.02yr avg
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Research Topics

Antifungal resistance and susceptibility(20), Chemical Synthesis and Analysis(19), Receptor Mechanisms and Signaling(19), Peptidase Inhibition and Analysis(15), Reproductive tract infections research(13)

Publications169 total

The molecular basis of intrinsic resistance to azoles in <i>Rhizopus arrhizus</i>
Antimicrobial Agents and Chemotherapy·2025· 1 citedOpen Access
A pilot study of re-purposing drugs to treat koalas with chlamydia
Scientific Reports·2025Open Access
Exploring Long Arm Amide-Linked Side Chains in the Design of Antifungal Azole Inhibitors of Sterol 14α-Demethylase (CYP51)
Journal of Medicinal Chemistry·2025· 3 citedOpen Access
Stimuli‐Responsive Prodrug Linkers That Simultaneously Release Cargo and Neutralize In Situ Generated (Aza)Quinone Methides
Chemistry - A European Journal·2025Open Access
The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus
Journal of Fungi·2024· 8 citedOpen Access
Covalent Isothiocyanate Inhibitors of Macrophage Migration Inhibitory Factor as Potential Colorectal Cancer Treatments
ChemMedChem·2024· 3 citedOpen Access
Synthesis and antifungal evaluation of novel triazole derivatives bearing a pyrazole-methoxyl moiety
European Journal of Medicinal Chemistry·2024· 6 citedOpen Access
Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor
ChemBioChem·2024· 3 citedOpen Access
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis
Cell chemical biology·2023· 18 citedOpen Access
Synthesis and Characterization of a Cannabinoid Type 2 Receptor Photoactivated Prodrug
ChemPhotoChem·2022· 2 citedOpen Access
Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of <i>Mycobacterium tuberculosis</i> Cytochrome <i>bd</i> Oxidase
ACS Medicinal Chemistry Letters·2022· 17 citedOpen Access
S-217622, a 3CL Protease Inhibitor and Clinical Candidate for SARS-CoV-2
Journal of Medicinal Chemistry·2022· 38 cited
An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis
Communications Biology·2022· 39 citedOpen Access
Structure-activity relationships of N-terminal variants of peptidomimetic tissue transglutaminase inhibitors
European Journal of Medicinal Chemistry·2022· 19 citedOpen Access
Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against Helicobacter pylori: A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles
Pharmaceutics·2022· 6 citedOpen Access
Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host
Journal of Fungi·2022· 16 citedOpen Access
Covalent cannabinoid receptor ligands – structural insight and selectivity challenges
RSC Medicinal Chemistry·2022· 1 citedOpen Access
Bifunctional Tools to Study Adenosine Receptors
Topics in medicinal chemistry·2022· 5 cited
Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia
European Journal of Medicinal Chemistry·2021· 6 citedOpen Access
Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate
Journal of Fungi·2021· 10 citedOpen Access
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Frequent Co-authors

David P. Fairlie(20), Brian C. Monk(10), Mikhail V. Keniya(6), Robert C. Reid(6), Giovanni Abbenante(5), Matthew P. Glenn(5), A. Sagatova(5), Rajni K. Wilson(5), Tessa Nall(4), Richard D. Cannon(4), M. Sabherwal(4), Richard J. Lewis(3), Wilhelmina M. Huston(3), Darren R. March(3), Martin J. Stoermer(3), Jennifer L. Martin(3), Leonard K. Pattenden(3), Michael J. Kelso(3), Bernhard Pfeiffer(2), Rajesh Lamichhane(2)