John Ziebuhr

Justus-Liebig-Universität Gießen — Germany

Medicine · Health Sciences

61h-index31.2kcitations162works2.42yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(69), Viral gastroenteritis research and epidemiology(68), Animal Virus Infections Studies(62), Viral Infections and Immunology Research(23), Virus-based gene therapy research(15)

Publications157 total

RAAS antagonists dampen the SARS-CoV-2 infection in ex-vivo cultured human precision-cut lung slices
Respiratory Research·2026Open Access
PERK inhibition rewires translational and CMGC protein kinase networks into an antiviral state
2025Open Access
Targeting sphingolipid metabolism: inhibition of neutral sphingomyelinase 2 impairs coronaviral replication organelle formation
mBio·2025Open Access
1H, 13C and 15N chemical shift assignment for stem-loop 5a from the 5‘UTR of HCoV-229E
Biomolecular NMR Assignments·2025Open Access
Distinct negative-sense RNA viruses induce a common set of transcripts encoding proteins forming an extensive network
Journal of Virology·2024· 2 citedOpen Access
Potent anti-coronaviral activity of pateamines and new insights into their mode of action
Heliyon·2024· 3 citedOpen Access
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
UNC Libraries·2024· 1 citedOpen Access
Alpha- and betacoronavirus cis-acting RNA elements
Current Opinion in Microbiology·2024· 4 citedOpen Access
Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients
Frontiers in Cellular and Infection Microbiology·2024· 6 citedOpen Access
Identification of Dual Inhibitors Targeting Main Protease (M<sup>pro</sup>) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents
ACS Medicinal Chemistry Letters·2024· 6 citedOpen Access
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2
Communications Chemistry·2024· 7 citedOpen Access
Potent Anti-Coronaviral Activity of Pateamines and New Insights into Their Mode of Action
SSRN Electronic Journal·2024Open Access
Conserved Characteristics of NMPylation Activities of Alpha- and Betacoronavirus NiRAN Domains
Journal of Virology·2023· 11 citedOpen Access
Peptidyl Nitroalkene Inhibitors of Main Protease (Mpro) rationalized by Computational/Crystallographic Investigations as Antivirals against SARS-CoV-2
2023Open Access
A Novel Insertion in the Hepatitis B Virus Surface Protein Leading to Hyperglycosylation Causes Diagnostic and Immune Escape
Viruses·2023· 10 citedOpen Access
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors
European Journal of Medicinal Chemistry·2022· 24 citedOpen Access
Reply to: The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein
Nature Communications·2022· 6 citedOpen Access
Thapsigargin: key to new host-directed coronavirus antivirals?
Trends in Pharmacological Sciences·2022· 19 citedOpen Access
IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection
Viruses·2022· 27 citedOpen Access
Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity
Viruses·2022· 16 citedOpen Access
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Frequent Co-authors

Alexander E. Gorbalenya(17), Eric J. Snijder(12), Volker Thiel(12), Stuart G. Siddell(7), Christian Drosten(6), Leo L. M. Poon(5), Nadja Karl(5), Ramakanth Madhugiri(5), Susan C. Baker(4), Chris Lauber(4), Benjamin W. Neuman(4), Konstantin A. Ivanov(4), Ákos Putics(4), Tobias Hertzig(4), Christin Müller(4), Ralph S. Baric(3), Raoul J. de Groot(3), Anastasia Gulyaeva(3), Stanley Perlman(3), Roland Züst(3)