Alexander E. Gorbalenya

Leiden University Medical Center — Netherlands

Agricultural and Biological Sciences · Life Sciences

94h-index41.8kcitations241works6.72yr avg
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Research Topics

Animal Virus Infections Studies(97), Viral gastroenteritis research and epidemiology(89), Viral Infections and Immunology Research(78), Plant Virus Research Studies(54), Bacteriophages and microbial interactions(47)

Publications239 total

A large replicase of nidovirus-like complexity in a putative RNA virus order <i>“Quisvirales”</i> expands the known diversity of helicase superfamilies
2026Open Access
Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses
Proceedings of the National Academy of Sciences·2025· 10 citedOpen Access
Intraspecific variation of the hedgehog arteriviruses, which may constitute a new genus in the subfamily Heroarterivirinae of the family Arteriviridae
Archives of Virology·2025· 1 citedOpen Access
Surveillance of coronaviruses in wild aquatic birds in Hong Kong: expanded genetic diversity and discovery of novel subgenus in the <i>Deltacoronavirus</i>
Virus Evolution·2025· 1 citedOpen Access
RNA genome expansion up to 64 kb in nidoviruses is host constrained and associated with new modes of replicase expression
2024· 4 citedOpen Access
PLOS Pathogens expanding horizons
PLoS Pathogens·2024Open Access
Deep mining of the Sequence Read Archive reveals major genetic innovations in coronaviruses and other nidoviruses of aquatic vertebrates
PLoS Pathogens·2024· 31 citedOpen Access
What’s what in a pandemic? Virus, disease, and societal disaster must be differentiated
PLoS Biology·2023Open Access
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition
mBio·2022· 56 citedOpen Access
Genome-wide diversity of Zika virus: Exploring spatio-temporal dynamics to guide a new nomenclature proposal
Virus Evolution·2022· 13 citedOpen Access
Editorial overview: Virus bioinformatics - empowering genomics of pathogens, viromes, and the virosphere across divergence scales
Current Opinion in Virology·2021· 1 cited
Translating genomic exploration of the family Polyomaviridae into confident human polyomavirus detection
iScience·2021· 5 citedOpen Access
Bioinformatics of virus taxonomy: foundations and tools for developing sequence-based hierarchical classification
Current Opinion in Virology·2021· 30 citedOpen Access
Deep mining of the Sequence Read Archive reveals bipartite coronavirus genomes and inter-family Spike glycoprotein recombination
2021· 10 citedOpen Access
ICTV Virus Taxonomy Profile: Arteriviridae 2021
Journal of General Virology·2021· 216 citedOpen Access
Science, not speculation, is essential to determine how SARS-CoV-2 reached humans
The Lancet·2021· 27 citedOpen Access
SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse
Nature Microbiology·2021· 311 citedOpen Access
Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution
Virology·2021· 50 citedOpen Access
Recognizing species as a new focus of virus research
PLoS Pathogens·2021· 26 citedOpen Access
Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit
Proceedings of the National Academy of Sciences·2021· 128 citedOpen Access
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Frequent Co-authors

Eric J. Snijder(13), John Ziebuhr(11), Eugene V. Koonin(11), Andrew M. Q. King(7), Alexei P. Donchenko(7), Vladimir M. Blinov(7), Leo L. M. Poon(6), Nick J. Knowles(6), Jens H. Kuhn(6), Peter Simmonds(6), Bruno Canard(6), Elliot J. Lefkowitz(5), Balázs Harrach(5), Mart Krupovìč(5), Max L. Nibert(5), Sead Sabanadzovic(5), Arvind Varsani(5), F. Murilo Zerbini(5), Andrew J. Davison(5), Christian Drosten(4)