Lars Christian B. Rønn

Lundbeck (Denmark) — Denmark

Neuroscience · Life Sciences

28h-index2.5kcitations46works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(19), Ion channel regulation and function(12), Receptor Mechanisms and Signaling(7), Cardiac electrophysiology and arrhythmias(6), Neurogenesis and neuroplasticity mechanisms(6)

Publications46 total

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain
Science Advances·2019· 58 citedOpen Access
The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin
Bioorganic & Medicinal Chemistry Letters·2017· 13 citedOpen Access
Inhibition of the potassium channel K Ca 3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
European Journal of Pharmacology·2016· 32 cited
NS19504: A Novel BK Channel Activator with Relaxing Effect on Bladder Smooth Muscle Spontaneous Phasic Contractions
Journal of Pharmacology and Experimental Therapeutics·2014· 23 citedOpen Access
Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor–ligand complex
Acta Crystallographica Section D Biological Crystallography·2014· 34 citedOpen Access
The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin
Bioorganic & Medicinal Chemistry Letters·2013· 44 citedOpen Access
Selective Positive Modulator of Calcium-Activated Potassium Channels Exerts Beneficial Effects in a Mouse Model of Spinocerebellar Ataxia Type 2
Chemistry & Biology·2012· 145 citedOpen Access
Positive allosteric modulation of α4β2 nAChR agonist induced behaviour
Brain Research·2012· 41 cited
K<sub>v</sub>7 Positive Modulators Reduce Detrusor Overactivity and Increase Bladder Capacity in Rats
Basic & Clinical Pharmacology & Toxicology·2011· 33 cited
Effect of the SK/IK channel modulator 4,5‐dichloro‐1,3‐diethyl‐1,3‐dihydro‐benzoimidazol‐2‐one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle
British Journal of Urology·2011· 15 cited
Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder
European Journal of Pharmacology·2010· 62 cited
Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools
Experimental & Translational Stroke Medicine·2010· 6 citedOpen Access
Synaptic dysfunction in migraine: novel approaches for drug development [abstract]
MOspace Institutional Repository (University of Missouri)·2010Open Access
Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD
Proceedings of the National Academy of Sciences·2009· 113 citedOpen Access
NCAM in Long-Term Potentiation and Learning
Advances in experimental medicine and biology·2009· 11 cited
Erratum to “Chloride channel blockers inhibit iNOS expression and NO production in IFNγ-stimulated microglial BV2 cells” [Brain Res. 128 (2009) 15–24]
Brain Research·2009
Chloride channel blockers inhibit iNOS expression and NO production in IFNγ-stimulated microglial BV2 cells
Brain Research·2009· 10 cited
A Positive Modulator of KCa2 and KCa3 Channels, 4,5-Dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591), Inhibits Bladder Afferent Firing in Vitro and Bladder Overactivity in Vivo
Journal of Pharmacology and Experimental Therapeutics·2008· 36 cited
NCAM in Long-Term Potentiation and Learning
Neurochemical Research·2008· 2 cited
In Vivo Effects of the IKr Agonist NS3623 on Cardiac Electrophysiology of the Guinea Pig
Journal of Cardiovascular Pharmacology·2008· 32 cited
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Frequent Co-authors

Elisabeth Bock(14), Vladimir Berezin(12), Frederik Rode(8), Barbara P. Hartz(5), Arne Møller(5), Dorte Strøbæk(5), Palle Christophersen(4), Vladislav Soroka(4), Arne Holm(4), Katrine Kjær(4), Charlotte Hougaard(3), Flemming M. Poulsen(3), Anders Hay‐Schmidt(3), Jens D. Mikkelsen(3), Henrik H. Hansen(3), Jesper Kelsen(3), Jens Randel Nyengaard(3), Ibrahim Malik(3), Samsa Lindberg(3), Morten Langgård(3)