Tamás Szimler

Eötvös Loránd University — Hungary

Materials Science · Physical Sciences

4h-index22citations8works0.02yr avg
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Research Topics

Enzyme Structure and Function(3), Mass Spectrometry Techniques and Applications(2), Biochemical and Molecular Research(2), Tuberculosis Research and Epidemiology(1), Protein Structure and Dynamics(1)

Publications8 total

Comprehensive SAR analysis of actomyolytics, drug candidates targeting the actomyosin complex
European Journal of Medicinal Chemistry·2025Open Access
A versatile modular vector set for optimizing protein expression among bacterial, yeast, insect and mammalian hosts
PLoS ONE·2019· 4 citedOpen Access
New type of interaction between the SARAH domain of the tumour suppressor RASSF1A and its mitotic kinase Aurora A
Scientific Reports·2019· 4 citedOpen Access
Dual Role of the Active Site Residues of <i>Thermus thermophilus</i> 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure
Biochemistry·2016· 2 cited
Glutamate 270 plays an essential role in K<sup>+</sup>‐activation and domain closure of <i>Thermus thermophilus</i> isopropylmalate dehydrogenase
FEBS Letters·2014· 5 citedOpen Access
Drugs Against Mycobacterium tuberculosis 3-Isopropylmalate Dehydrogenase Can be Developed Using Homologous Enzymes as Surrogate Targets
Protein and Peptide Letters·2014· 2 cited
Structure of the E270A Mutant Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH
2014
Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase
FEBS Letters·2011· 5 citedOpen Access

Frequent Co-authors

Éva Gráczer(7), Péter Závodszky(7), Mária Vas(6), Dmitri I. Svergun(4), Anna Palló(3), Julianna Oláh(3), Petr V. Konarev(3), Angelo Merli(3), M.S. Weiss(3), András Bacsó(2), Barbara M. Végh(2), András Szilágyi(2), László Beinrohr(2), Adrienn Bodonyi(1), Dániel Györffy(1), I Hajdú(1), Márk Somogyi(1), Attila Baksa(1), Tamás Bakos(1), Katalin Paréj(1)