Angelo Merli

University of Parma — Italy

Materials Science · Physical Sciences

15h-index824citations39works0.02yr avg
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Research Topics

Enzyme Structure and Function(11), Hemoglobin structure and function(7), Biochemical and Molecular Research(7), Protein Structure and Dynamics(6), Microbial metabolism and enzyme function(6)

Publications38 total

Dual Role of the Active Site Residues of <i>Thermus thermophilus</i> 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure
Biochemistry·2016· 2 cited
The identification of an integral membrane, cytochrome c urate oxidase completes the catalytic repertoire of a therapeutic enzyme
Scientific Reports·2015· 24 citedOpen Access
Glutamate 270 plays an essential role in K<sup>+</sup>‐activation and domain closure of <i>Thermus thermophilus</i> isopropylmalate dehydrogenase
FEBS Letters·2014· 5 citedOpen Access
Structure of the E270A Mutant Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH
2014
Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis
FEBS Journal·2014· 20 citedOpen Access
Hyper <scp>I</scp>g<scp>E</scp> syndrome: anaphylaxis in a patient carrying the <scp>N</scp>567<scp>D </scp><i><scp>STAT</scp>3</i> mutation
Pediatric Allergy and Immunology·2014· 12 cited
Efficient Electron Transfer in a Protein Network Lacking Specific Interactions
Journal of the American Chemical Society·2011· 27 cited
Atomic level description of the domain closure in a dimeric enzyme: <i>Thermus thermophilus</i> 3-isopropylmalate dehydrogenase
Molecular BioSystems·2011· 13 cited
A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase
Journal of Biological Chemistry·2011· 65 citedOpen Access
Amicyanin Transfers Electrons from Methylamine Dehydrogenase to Cytochrome <i>c</i>-551i via a Ping-Pong Mechanism, not a Ternary Complex
Journal of the American Chemical Society·2010· 13 cited
Crystallization and preliminary X-ray diffraction analysis of various enzyme–substrate complexes of isopropylmalate dehydrogenase from<i>Thermus thermophilus</i>
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2010· 1 citedOpen Access
The complete reaction cycle of human phosphoglycerate kinase: The open binary complex with 3PG
2010
The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and ADP
2010
Structures of the G81A mutant form of the active chimera of (<i>S</i>)-mandelate dehydrogenase and its complex with two of its substrates
Acta Crystallographica Section D Biological Crystallography·2009· 10 citedOpen Access
Structural Comparison of Crystal and Solution States of the 138 kDa Complex of Methylamine Dehydrogenase and Amicyanin from <i>Paracoccus versutus</i>
Biochemistry·2009
Structural Comparison of Crystal and Solution States of the 138 kDa Complex of Methylamine Dehydrogenase and Amicyanin from <i>Paracoccus versutus</i>
Biochemistry·2008· 8 cited
Paracoccus versutus methylamine dehydrogenase in complex with amicyanin
2008
Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from<i>Alcaligenes faecalis</i><sup>,</sup>
Biochemistry·2006· 35 cited
Electron transfer in crystals of the binary and ternary complexes of methylamine dehydrogenase with amicyanin and cytochrome c551i as detected by EPR spectroscopy
JBIC Journal of Biological Inorganic Chemistry·2004· 15 cited
Catalysis and electron transfer in protein crystals: the binary and ternary complexes of methylamine dehydrogenase with electron acceptors
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2003· 15 cited
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Frequent Co-authors

Gian Luigi Rossi(16), Mária Vas(11), Éva Gráczer(7), Martino Bolognesi(6), Marcellus Ubbink(6), Péter Závodszky(6), M.S. Weiss(6), F. Scott Mathews(5), Paolo Ascenzi(4), Oliver Einsle(4), Victor L. Davidson(4), Davide Ferrari(4), Anna Palló(4), Julianna Oláh(4), Chiara Cavalieri(4), Matthew W. Bowler(3), Nikolai Biermann(3), Monica D. Vlasie(3), Tamás Szimler(3), Dmitri I. Svergun(3)