Matthias Bütikofer

University of Vienna — Austria

Chemistry · Physical Sciences

9h-index265citations21works3.82yr avg
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Research Topics

Advanced NMR Techniques and Applications(7), Protein Structure and Dynamics(6), Computational Drug Discovery Methods(6), SARS-CoV-2 and COVID-19 Research(4), Atomic and Subatomic Physics Research(4)

Publications21 total

<i>N</i>MR<sup>2</sup>-Based Drug Discovery Pipeline Presented on the Oncogenic Protein KRAS
Journal of the American Chemical Society·2025· 2 citedOpen Access
Rescaling NMR for a Larger Deployment in Drug Discovery: Hyperpolarization and Benchtop NMR as Potential Game‐Changers
Chemistry - Methods·2024· 3 citedOpen Access
Rapid Protein–Ligand Affinity Determination by Photoinduced Hyperpolarized NMR
Journal of the American Chemical Society·2024· 12 citedOpen Access
Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform
Magnetic Resonance·2024· 4 citedOpen Access
Comment on mr-2024-3
2024Open Access
Supplementary material to "An automated NMR platform with light-coupled cryogenic probes to detect low micromolar samples"
2024Open Access
An automated NMR platform with light-coupled cryogenic probes to detect low micromolar samples
2024· 2 citedOpen Access
Targeting the Main Protease (M<sup>pro</sup>, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies
ACS Chemical Biology·2024· 7 citedOpen Access
Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization
Angewandte Chemie International Edition·2023· 27 citedOpen Access
Fragment‐Screening und schnelle mikromolare Detektion mit einem Benchtop‐NMR‐Spektrometer ermöglicht durch photoinduzierte Hyperpolarisation
Angewandte Chemie·2023· 1 cited
Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR
Journal of the American Chemical Society·2023· 45 citedOpen Access
Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach
Journal of Natural Products·2023· 32 citedOpen Access
Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression
Communications Biology·2022· 21 citedOpen Access
Short Lecture “Natural products against SARS-CoV-2 or how to catch a butterfly?”
Planta Medica·2022
Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development
Angewandte Chemie·2022· 9 citedOpen Access
Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development
Angewandte Chemie International Edition·2022· 22 citedOpen Access
High-Mass Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Absolute Quantitation of Noncovalent Protein–Protein Binding Interactions
Analytical Chemistry·2021· 9 citedOpen Access
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications
Frontiers in Molecular Biosciences·2021· 53 citedOpen Access
Carbonyl Sulfide as a Prebiotic Activation Agent for Stereo- and Sequence-Selective, Amyloid-Templated Peptide Elongation
Origins of Life and Evolution of Biospheres·2019· 6 cited
Finanzierung von Nonprofit-Organisationen
2013· 2 cited
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Frequent Co-authors

Roland Riek(13), Felix Torres(10), Marie Jose Abi Saad(7), Julien Orts(7), Gabriela R. Stadler(5), Alois Renn(5), Nadide Altincekic(4), Ad Bax(4), S.L. Gande(4), Dhiman Ghosh(4), Kristaps Jaudzems(4), V.L. Linhard(4), Frank Löhr(4), Christian Richter(4), Angus J. Robertson(4), Harindranath Kadavath(4), Sophie Marianne Korn(3), Nusrat S. Qureshi(3), Martí Ninot‐Pedrosa(3), Fábio C. L. Almeida(3)