Roland Riek

ETH Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

82h-index34.7kcitations453works4.62yr avg
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Research Topics

Protein Structure and Dynamics(117), Alzheimer's disease research and treatments(98), Advanced NMR Techniques and Applications(71), Prion Diseases and Protein Misfolding(67), Parkinson's Disease Mechanisms and Treatments(59)

Publications453 total

Structural insights into copper and zinc binding to tau protein and the impact of metal binding on amyloid aggregation
Chemical Science·2026Open Access
FragmentScope - exploring the fragment space with learned surface representations
2025Open Access
Spermine modulation of Alzheimer’s Tau and Parkinson’s α-synuclein: implications for biomolecular condensation and neurodegeneration
Nature Communications·2025· 2 citedOpen Access
Multiple spin order generated by photo-CIDNP hyperpolarisation NMR
Molecular Physics·2025Open Access
Structural Insights and Functional Dynamics of β-Lactoglobulin Fibrils
Nano Letters·2025· 1 cited
Impurities in amyloid studies: The power of automated model building within a cautionary tale for structural biologists
Protein Science·2025Open Access
ATP Hydrolysis by α‐Synuclein Amyloids is Mediated by Enclosing β‐Strand
Advanced Science·2025Open Access
Structure-function relationship of alpha-synuclein fibrillar polymorphs derived from distinct synucleinopathies
Repository for Publications and Research Data (ETH Zurich)·2025Open Access
Alpha-synuclein fibrils induce budding of mitochondrial-derived vesicles
2025Open Access
Structure-function relationship of alpha-synuclein fibrillar polymorphs derived from distinct synucleinopathies
2025· 1 citedOpen Access
De novo design of phosphorylation-induced protein switches for synthetic signaling in cells
2025Open Access
The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions
Advanced Science·2025· 3 citedOpen Access
Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria
Nature Communications·2025· 2 citedOpen Access
Super-resolution triple-resonance NMR spectroscopy for the sequential assignment of proteins
Science Advances·2025Open Access
Machine learning in NMR spectroscopy
Progress in Nuclear Magnetic Resonance Spectroscopy·2025· 6 citedOpen Access
Revisiting the measurement of a quantum mechanical experiment by an Ehrenfest theorem-based Fourier Transformation
Journal of Physics Conference Series·2025Open Access
An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ
npj Parkinson s Disease·2025· 4 citedOpen Access
<i>N</i>MR<sup>2</sup>-Based Drug Discovery Pipeline Presented on the Oncogenic Protein KRAS
Journal of the American Chemical Society·2025· 2 citedOpen Access
TNF- <i>α</i> disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson’s Disease patients
2025· 1 citedOpen Access
TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson’s Disease patients
Repository for Publications and Research Data (ETH Zurich)·2025Open Access
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Frequent Co-authors

Kurt Wüthrich(18), Gerhard Wider(10), Samir K. Maji(8), Simone Hornemann(7), David Eisenberg(7), Rudi Glockshuber(6), Konstantin Pervushin(5), Martin Billeter(5), Beat H. Meier(5), Thorsten Lührs(4), Silvia Campioni(4), M.R. Sawaya(4), David Schubert(3), Jean Rivier(3), Juan Gerez(3), Ashutosh Kumar(3), Peter Güntert(3), Henning Stahlberg(3), Jason Greenwald(3), Dhiman Ghosh(3)