Simone Hornemann

University of Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index8.5kcitations151works4.52yr avg
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Research Topics

Prion Diseases and Protein Misfolding(91), Trace Elements in Health(40), Neurological diseases and metabolism(32), Alzheimer's disease research and treatments(13), Enzyme Structure and Function(13)

Publications151 total

Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity
PLoS Biology·2025Open Access
The Bone Morphogenetic Pathway Controls the Uptake of Infectious Prions
2025Open Access
Later meal timing in relation to an individual internal clock is heritable and associated with lower insulin sensitivity
Diabetologie und Stoffwechsel·2025
Non-invasive telemonitoring programs for patients with chronic heart failure: A systematic review and meta-analysis of randomized controlled trials
Journal of Telemedicine and Telecare·2024· 3 cited
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes
Nature Biomedical Engineering·2024· 22 citedOpen Access
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
EMBO Molecular Medicine·2024· 10 citedOpen Access
Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic
PLoS ONE·2024· 1 citedOpen Access
Author Reply to Peer Reviews of The ASC inflammasome adapter governs the extent of peripheral SAA-derived protein aggregate deposition in inflammation-induced amyloidosis
2024
A screen of alkaline and oxidative formulations for their inactivation efficacy of metal surface adsorbed prions using a steel-bead seed amplification assay
2023· 1 citedOpen Access
WITHDRAWN: The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity
2023Open Access
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region
iScience·2023· 12 citedOpen Access
An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation
The EMBO Journal·2022· 9 citedOpen Access
Author Reply to Peer Reviews of An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
2022
A conformational switch controlling the toxicity of the prion protein
Nature Structural & Molecular Biology·2022· 31 citedOpen Access
Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing
2022· 22 citedOpen Access
Concordance of cerebrospinal fluid real‐time quaking‐induced conversion across the European Creutzfeldt–Jakob Disease Surveillance Network
European Journal of Neurology·2022· 21 citedOpen Access
An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
2022· 3 citedOpen Access
Large-scale seroepidemiology uncovers nephro-urological pathologies in persons with tau autoimmunity
2021· 4 citedOpen Access
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Science Advances·2021· 31 citedOpen Access
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference
PLoS Pathogens·2021· 9 citedOpen Access
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Frequent Co-authors

Adriano Aguzzi(30), Kurt Wüthrich(19), Roland Riek(11), Rudi Glockshuber(11), Petra Schwarz(9), Christina J. Sigurdson(8), K. Peter R. Nilsson(8), Gerhard Wider(6), Regina Reimann(6), Martin Billeter(5), Giuseppe Manco(5), Assunta Senatore(5), Silvia Sorce(5), Tuomas P. J. Knowles(5), Magdalini Polymenidou(4), Per Hammarström(4), Mario Nuvolone(4), Tiziana Sonati(4), Jeppe Falsig(4), U. Herrmann(4)