Srinivasan P Venkatachalan

Goldfinch Bio (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index338citations15works0.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(6), Neuroscience and Neuropharmacology Research(4), Ion channel regulation and function(3), Renal and related cancers(3), Pluripotent Stem Cells Research(2)

Publications15 total

Transplanted organoids empower human preclinical assessment of drug candidate for the clinic
Science Advances·2022· 25 citedOpen Access
Discovery and Optimization of Highly Selective Inhibitors of CDK5
Journal of Medicinal Chemistry·2022· 24 citedOpen Access
Cell engineering method using fluorogenic oligonucleotide signaling probes and flow cytometry
Biotechnology Letters·2021· 4 citedOpen Access
SO038A TRANSLATIONAL KIDNEY ORGANOID SYSTEM BOLSTERS HUMAN RELEVANCE OF CLINICAL DEVELOPMENT CANDIDATE
Nephrology Dialysis Transplantation·2020
A translational kidney organoid system bolsters human relevance of clinical development candidate
2019· 2 citedOpen Access
Structural Link between γ-Aminobutyric Acid Type A (GABAA) Receptor Agonist Binding Site and Inner β-Sheet Governs Channel Activation and Allosteric Drug Modulation
Journal of Biological Chemistry·2012· 25 citedOpen Access
Identification of a fluorescent general anesthetic, 1-aminoanthracene
Proceedings of the National Academy of Sciences·2009· 51 citedOpen Access
A conserved salt bridge critical for GABA <sub>A</sub> receptor function and loop C dynamics
Proceedings of the National Academy of Sciences·2008· 66 citedOpen Access
An intrasubunit salt‐bridge linking Loop A and Loop 2 is critical for GABAA receptor activation
The FASEB Journal·2008· 1 cited
Optimized expression vector for ion channel studies in Xenopus oocytes and mammalian cells using alfalfa mosaic virus
Pflügers Archiv - European Journal of Physiology·2006· 58 citedOpen Access
Micromechanical measurement of membrane receptor binding for label-free drug discovery
Biosensors and Bioelectronics·2004· 31 cited
Identification of critical residues in loop E in the 5-HT3ASR binding site
BMC Biochemistry·2002· 34 citedOpen Access
Functional group interactions of a 5-HT3R antagonist
BMC Biochemistry·2002· 17 citedOpen Access
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BMC Biochemistry·2002
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BMC Biochemistry·2002Open Access

Frequent Co-authors

Prasad Joshi(5), Marvin K. Schulte(5), Padmavati Venkataraman(4), Mani Muthalagi(4), G. Malojcic(4), Xin-Ru Pan-Zhou(4), Mark W. Ledeboer(4), Jean-Christophe Harmange(4), Cynthia Czajkowski(3), Amy Westerling-Bui(3), Eva M. Fast(3), Thomas W. Soare(3), Michael DeRan(3), Alyssa Fanelli(3), Sergii Kyrychenko(3), Hien G. Hoang(3), Grinal M. Corriea(3), Maolin Yu(3), Matthew H. Daniels(3), Maheswarareddy Emani(3)