Gene Hopping

The University of Queensland — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index648citations22works0.32yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(10), Chemical Synthesis and Analysis(8), Protein Structure and Dynamics(4), Alzheimer's disease research and treatments(4), Receptor Mechanisms and Signaling(4)

Publications22 total

The structural integrity of human TFF1 under reducing conditions
Redox Biology·2025Open Access
PeptideMiner—neuropeptide discovery across the animal kingdom
GigaScience·2025· 1 citedOpen Access
The Structural Integrity of Disulfide Bonds in Tff1 Under Reducing Conditions
SSRN Electronic Journal·2024Open Access
A TfR-Binding Cystine-Dense Peptide Promotes Blood–Brain Barrier Penetration of Bioactive Molecules
Journal of Molecular Biology·2020· 34 citedOpen Access
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
Science Translational Medicine·2020· 40 cited
Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging
Anticancer Research·2018
Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence
Journal of Molecular Biology·2016· 55 citedOpen Access
Nature versus design: the conformational propensities of d-amino acids and the importance of side chain chirality
Protein Engineering Design and Selection·2014· 38 citedOpen Access
Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors
Biochemical Pharmacology·2014· 22 cited
Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers
eLife·2014· 79 citedOpen Access
Author response: Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers
2014Open Access
Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid Systems
ACS Medicinal Chemistry Letters·2013· 25 citedOpen Access
Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine‐Assisted Folding
Angewandte Chemie International Edition·2011· 95 cited
Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine‐Assisted Folding
Angewandte Chemie·2011· 21 cited
Benzhydrylamine linker grafting: a strategy for the improved synthesis of <i>C</i>‐terminal peptide amides
Journal of Peptide Science·2010· 4 cited
Rapid Access to ?-Conotoxin Chimeras using Native Chemical Ligation
Australian Journal of Chemistry·2009· 6 cited
AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity
The EMBO Journal·2007· 156 citedOpen Access
Structural studies of AChBP, a soluble nicotinic acetylcholine receptor homolog, in complex with novel ligands
Queensland's institutional digital repository (The University of Queensland)·2007
Synthesis, Structure and Activity of Disulfide-Rich Conus Peptides
2006· 1 cited
Point Mutations of Alpha-Conotoxin PnIA to Characterise Subtypes of Human and Rat Nicotinic Acetylcholine Receptors
Peptide science : proceedings of the ... Japanese Peptide Symposium·2005
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Frequent Co-authors

Paul F. Alewood(9), Richard J. Lewis(5), Valerie Daggett(5), David J. Adams(4), Jackson Kellock(4), Byron Caughey(4), Simon T. Nevin(3), Emily J. Girard(3), Andrew J. Mhyre(3), James M. Olson(3), Markus Muttenthaler(3), Sébastien Dutertre(2), Chris Ulens(2), René van Elk(2), Christina I. Schroeder(2), Annette Nicke(2), August B. Smit(2), Aline D. de Araujo(2), Brid Callaghan(2), Norelle L. Daly(2)