Simon T. Nevin

University of Queensland — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.1kcitations44works0.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(27), Receptor Mechanisms and Signaling(21), Ion channel regulation and function(10), Chemical Synthesis and Analysis(8), Neuropeptides and Animal Physiology(7)

Publications44 total

Functional modulation of the human voltage-gated sodium channel Na<sub>V</sub>1.8 by auxiliary β subunits
Channels·2020· 6 citedOpen Access
Functional modulation of the human voltage-gated sodium channel Na<sub>V</sub>1.8 by auxiliary β subunits
Figshare·2020Open Access
Functional Modulation of the Human Voltage-Gated Sodium Channel Na<sub>V</sub>1.8 by Auxiliary β Subunits
Figshare·2020Open Access
On-Resin Strategy to Label α-Conotoxins: Cy5-RgIA, a Potent α9α10 Nicotinic Acetylcholine Receptor Imaging Probe
Australian Journal of Chemistry·2019· 7 citedOpen Access
Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors
Biochemical Pharmacology·2014· 22 cited
Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine‐Assisted Folding
Angewandte Chemie International Edition·2011· 95 cited
Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine‐Assisted Folding
Angewandte Chemie·2011· 21 cited
Structure and Activity of α-Conotoxin PeIA at Nicotinic Acetylcholine Receptor Subtypes and GABAB Receptor-coupled N-type Calcium Channels
Journal of Biological Chemistry·2011· 46 citedOpen Access
Conotoxins - blueprints for GPCR drug discovery?
Queensland's institutional digital repository (The University of Queensland)·2011
A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain
Pain·2010· 86 cited
Innentitelbild: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. 37/2010)
Angewandte Chemie·2010· 1 cited
Inside Cover: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. Int. Ed. 37/2010)
Angewandte Chemie International Edition·2010· 1 citedOpen Access
The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain
Angewandte Chemie·2010· 48 cited
The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain
Angewandte Chemie International Edition·2010· 311 cited
Stabilization of α-Conotoxin AuIB: Influences of Disulfide Connectivity and Backbone Cyclization
Antioxidants and Redox Signaling·2010· 43 cited
Solving the α-Conotoxin Folding Problem: Efficient Selenium-Directed On-Resin Generation of More Potent and Stable Nicotinic Acetylcholine Receptor Antagonists
Journal of the American Chemical Society·2010· 132 cited
Scanning Mutagenesis of α-Conotoxin Vc1.1 Reveals Residues Crucial for Activity at the α9α10 Nicotinic Acetylcholine Receptor
Journal of Biological Chemistry·2009· 84 citedOpen Access
Inhibition of Neuronal Nicotinic Acetylcholine Receptor Subtypes by α-Conotoxin GID and Analogues
Journal of Biological Chemistry·2008· 41 citedOpen Access
Low molecular weight contaminants in commercial preparations of plasmin and t‐PA activate neurons
Journal of Thrombosis and Haemostasis·2008· 8 cited
Tissue‐type plasminogen activator requires a co‐receptor to enhance NMDA receptor function
Journal of Neurochemistry·2008· 119 citedOpen Access
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Frequent Co-authors

David J. Adams(28), David J. Craik(24), Norelle L. Daly(17), Richard J. Clark(15), Paul F. Alewood(11), Richard J. Lewis(10), Jonas E. Jensen(5), Markus Muttenthaler(5), Annette Nicke(5), Brid P. Callaghan(4), Anton A. Grishin(4), MacDonald J. Christie(4), P.F. Alewood(4), Justine L. Haddrill(4), L. Dempster(3), Peter G. Noakes(3), André L. Samson(3), Robert L. Medcalf(3), Brid Callaghan(3), Gene Hopping(3)