David J. Craik

Australian Research Council — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

112h-index52.3kcitations1.4kworks4.92yr avg
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Research Topics

Biochemical and Structural Characterization(557), Toxin Mechanisms and Immunotoxins(198), Glycosylation and Glycoproteins Research(196), Phytoplasmas and Hemiptera pathogens(195), Nicotinic Acetylcholine Receptors Study(193)

Publications1.4k total

Rational Design of Plant-Derived Protein Ligases with Altered Substrate Specificity
Biochemistry·2026
α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis
International Journal of Biological Macromolecules·2026
Progress and Challenges in the Biosynthesis and Chemical Synthesis of Lasso Peptides
Journal of the American Chemical Society·2026
MACROCYCLIC AND STABILIZED DYNORPHIN PEPTIDES AS POTENT ANALGESICS FOR IBD PAIN MANAGEMENT
Gastroenterology·2026
MACROCYCLIC AND STABILIZED DYNORPHIN PEPTIDES AS POTENT ANALGESICS FOR IBD PAIN MANAGEMENT
Inflammatory Bowel Diseases·2026
Combining Bioactive Cell-Penetrating Peptides and Vemurafenib to Produce Peptide–Drug Conjugates with Activity Against Drug-Resistant Melanoma Cells
Journal of Medicinal Chemistry·2025· 1 cited
Discovery of insecticidal cyclotides from the African plants Allexis batangae and Allexis obanensis
Industrial Crops and Products·2025Open Access
Where Have You Been? Backtracking Microplastic to Its Source Using the Biomolecular Composition of the Ecocorona
Environmental Science & Technology·2025· 3 citedOpen Access
Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15–GFRaL–RET Complex Cell Signaling
Journal of Medicinal Chemistry·2025· 1 cited
Nickel‐Catalyzed Cascade C–H Alkynylation/Hydroamination of Free Benzylamines for the Synthesis of Substituted <scp> 1 <i>H</i> </scp> ‐Isoindoles Using a Transient Directing Group Strategy
Chinese Journal of Chemistry·2025· 1 cited
Mixed-Chirality Prohibitin Peptide: D-(RLARLAR)2 Enhances Stability and <i>In Vivo</i> Effects on Obesity
Journal of the American Chemical Society·2025
Asparaginyl Ligases with Engineered Substrate Specificity for Controlled, Sequential Transpeptidation Reactions
Journal of the American Chemical Society·2025· 3 citedOpen Access
Exploring Use of a Protein Cage System for Producing Bioactive Peptides in <i>Escherichia coli</i>
Microbial Biotechnology·2025Open Access
Cyclization of the Analgesic α‐Conotoxin Vc1.1 With a Non‐Natural Linker: Effects on Structure, Stability, and Bioactivity
Journal of Peptide Science·2025· 1 citedOpen Access
An Orthogonal Protection Strategy for the Synthesis of Conotoxins Containing Three Disulfide Bonds
Marine Drugs·2025· 4 citedOpen Access
Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an <i>Ex Vivo</i> Model
ACS Pharmacology & Translational Science·2025· 3 cited
Selective Inhibition of Rat α7 Nicotinic Acetylcholine Receptors by LvID, a Newly Characterized α4/7-Conotoxin from <i>Conus lividus</i>
Journal of Medicinal Chemistry·2025· 1 cited
Cell-Penetrating Cyclic and Disulfide-Rich Peptides Are Privileged Molecular Scaffolds for Intracellular Targeting
Biochemistry·2025· 3 cited
Cover Feature: Recombinant Production of The Cyclotide Kalata B1 by Conditional Split Inteins (ChemBioChem 4/2025)
ChemBioChem·2025Open Access
The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefs
Biological Conservation·2025· 10 citedOpen Access
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Frequent Co-authors

Norelle L. Daly(14), Quentin Kaas(8), Marilyn A. Anderson(7), K. Johan Rosengren(7), Paul F. Alewood(6), Ulf Göransson(5), Clement Waine(5), Richard J. Clark(5), David J. Adams(5), Conan K. Wang(5), Michelle L. Colgrave(4), Richard J. Lewis(4), David C. Ireland(4), Ivana Saska(4), Christian W. Gruber(3), David P. Fairlie(3), Cameron V. Jennings(3), Sébastien Dutertre(3), Simon T. Nevin(3), Manuel R. Plan(3)