Jitka Malčíková

Central European Institute of Technology — Czech Republic

Medicine · Health Sciences

22h-index2.2kcitations265works7.02yr avg
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Research Topics

Chronic Lymphocytic Leukemia Research(203), Lymphoma Diagnosis and Treatment(56), Cancer-related Molecular Pathways(46), Immunodeficiency and Autoimmune Disorders(34), Glycosylation and Glycoproteins Research(30)

Publications265 total

Detection of clinically relevant variants in the <i>TP53</i> gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL
HemaSphere·2025· 3 citedOpen Access
Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell <scp>RNA</scp> sequencing
Molecular Oncology·2024· 3 citedOpen Access
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—2024 update
Leukemia·2024· 22 citedOpen Access
Author response for "Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell &lt;scp&gt;RNA&lt;/scp&gt; sequencing"
2024
Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment‐naïve CLL patients
British Journal of Haematology·2023Open Access
Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)
Blood·2023Open Access
Laboratories Can Reliably Detect Clinically Relevant Variants in the <i>TP53</i> Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL
Blood·2023· 1 citedOpen Access
P602: SINGLE-CELL RNA-SEQUENCING ENABLES TRACKING AND CHARACTERIZATION OF RARE CLL CELLS WITH THE POTENTIAL TO CAUSE REFRACTORINESS.
HemaSphere·2023Open Access
How to clinically interpret the results of TP53 analyses in chronic lymphocytic leukaemia in the context of available therapeutic regimens
Transfuze a hematologie dnes·2023
Editorial: Biology and treatment of high-risk CLL
Frontiers in Oncology·2023· 1 citedOpen Access
Opinion: What defines high-risk CLL in the post-chemoimmunotherapy era?
Frontiers in Oncology·2023· 2 citedOpen Access
Biology and Treatment of High-Risk CLL
Frontiers research topics·2023
Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon <scp>DNA</scp> damage
Molecular Oncology·2022· 3 citedOpen Access
Author response for "Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage"
2022
P608: DISTINCT P53 PHOSPHORYLATION PATTERNS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS ARE REFLECTED IN CIRCUMJACENT PATHWAYS’ ACTIVATION UPON DNA DAMAGE
HemaSphere·2022Open Access
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
BMC Cancer·2022· 3 citedOpen Access
Low-burden <i>TP53</i> mutations in CLL: clinical impact and clonal evolution within the context of different treatment options
Blood·2021· 50 citedOpen Access
Minor-clone TP53 mutations in CLL patients entering first-line treatment: clonal evolution and clinical impact.
2020
PRIMA-1MET cytotoxic effect correlates with p53 protein reduction in TP53-mutated chronic lymphocytic leukemia cells
Leukemia Research·2019· 9 cited
PS1137 COMPLEX STRUCTURAL VARIANTS LEAD TO GENE INACTIVATION RATHER THAN EXPRESSION OF DE NOVO FUSION GENES IN CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere·2019Open Access
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Frequent Co-authors

Šárka Pospı́šilová(41), Martin Trbušek(31), Jiřı́ Mayer(26), Michael Doubek(23), Yvona Brychtová(21), Jana Šmardová(19), Boris Tichý(18), Karla Plevová(17), Šárka Pavlová(14), Hana Skuhrová Francová(10), Marek Mráz(10), Jana Kotašková(9), Thorsten Zenz(8), Κώστας Σταματόπουλος(8), Paolo Ghia(8), Stephan Stilgenbauer(8), Nikola Tom(8), Veronika Navrkalová(8), Lenka Radová(7), Arnon P. Kater(6)