Aizpea Zubia

University of the Basque Country — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index296citations20works0.02yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(8), Protein Degradation and Inhibitors(6), Peptidase Inhibition and Analysis(5), Chemical Synthesis and Analysis(4), Crystallization and Solubility Studies(4)

Publications20 total

Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia
Experimental and Molecular Therapeutics·2019
Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia
Cancer Research·2019
Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia
Blood·2018· 1 cited
<i>In vitro</i> and <i>in vivo</i> activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma
Haematologica·2018· 18 citedOpen Access
Development and validation of a LC‐MS assay for the quantification of ikh12 a novel anti‐tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study
Biomedical Chromatography·2015
Design, Synthesis, and Functional Evaluation of Leukocyte Function Associated Antigen-1 Antagonists in Early and Late Stages of Cancer Development
Journal of Medicinal Chemistry·2013· 25 citedOpen Access
Abstract C46: Design, synthesis, and functional evaluation of leukocyte-function associated antigen-1 (LFA-1) antagonists in early and late stages of cancer development.
Molecular Cancer Therapeutics·2011
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity
Oncogene·2009· 22 cited
Pharmacokinetics and tissue distribution of Kendine 91, a novel histone deacetylase inhibitor, in mice
Cancer Chemotherapy and Pharmacology·2008· 13 cited
Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of Kendine 91, a novel histone deacetylase inhibitor, in mice plasma and tissues: Application to a pharmacokinetic study
Journal of Chromatography B·2008· 7 cited
Solvent-Free Thermal and Microwave-Assisted [3 + 2] Cycloadditions between Stabilized Azomethine Ylides and Nitrostyrenes. An Experimental and Theoretical Study
The Journal of Organic Chemistry·2007· 89 cited
CCDC 627618: Experimental Crystal Structure Determination
The Cambridge Structural Database·2007Open Access
CCDC 609980: Experimental Crystal Structure Determination
The Cambridge Structural Database·2007Open Access
Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α<sub>4</sub>β<sub>1</sub>‐Integrin‐Mediated Hepatic Melanoma Metastasis
Angewandte Chemie International Edition·2005· 70 cited
Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α<sub>4</sub>β<sub>1</sub>‐Integrin‐Mediated Hepatic Melanoma Metastasis
Angewandte Chemie·2005· 15 cited
CCDC 252339: Experimental Crystal Structure Determination
The Cambridge Structural Database·2005Open Access
171 Unnatural small molecule mimic of VLA-4-binding VCAM-1 epitope inhibits the intravascular adhesion and proliferation of metastatic melanoma cells
European Journal of Cancer Supplements·2004
Quantitative Evaluation of the Catalytic Activity of Dendrimers with Only One Active Center at the Core:  Application to the Nitroaldol (Henry) Reaction
Journal of the American Chemical Society·2004· 33 cited
CCDC 176043: Experimental Crystal Structure Determination
The Cambridge Structural Database·2002Open Access
(2<i>S</i>*,3<i>R</i>*,4<i>S</i>*,5<i>R</i>*)-3-(<i>S</i>*-1-Benzyloxyethyl)-4-methyl-4-nitro-5-phenylproline methyl ester
Acta Crystallographica Section E Structure Reports Online·2001· 3 cited

Frequent Co-authors

Fernando P. Cossío(14), Dorleta Otaegui(9), Eneko Aldaba(7), Ana Arrieta(6), Yosu Vara(6), Silvia Vivanco(5), Begoña Lecea(5), Tahl Zimmerman(5), Fernando Vidal‐Vanaclocha(5), Eider San Sebastián(5), Manel Esteller(5), Lorea Mendoza(4), María Berdasco(4), Montserrat Pérez-Salvia(4), Carme Masdeu(4), Pere Llinàs‐Arias(4), Margalida Rosselló-Tortella(4), Fernando Setién(4), Alberto Villanueva(4), Eva González‐Barca(4)