David B. Krizman

United Therapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index5.2kcitations101works0.02yr avg
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Research Topics

Molecular Biology Techniques and Applications(25), Advanced Proteomics Techniques and Applications(17), Monoclonal and Polyclonal Antibodies Research(13), Cancer Genomics and Diagnostics(11), Cancer, Hypoxia, and Metabolism(8)

Publications101 total

121 Unlocking the antigenic proteome in clinical cancer tissue to enable personalized cancer immunotherapy
Regular and Young Investigator Award Abstracts·2025Open Access
Supplementary Data from Proteomic Analysis of Laser-Captured Paraffin-Embedded Tissues: A Molecular Portrait of Head and Neck Cancer Progression
2023Open Access
Data from Proteomic Analysis of Laser-Captured Paraffin-Embedded Tissues: A Molecular Portrait of Head and Neck Cancer Progression
2023Open Access
Data from Proteomic Analysis of Laser-Captured Paraffin-Embedded Tissues: A Molecular Portrait of Head and Neck Cancer Progression
2023Open Access
Supplementary Data from Proteomic Analysis of Laser-Captured Paraffin-Embedded Tissues: A Molecular Portrait of Head and Neck Cancer Progression
2023Open Access
Supplementary Material for: Application of a Global Proteomic Approach to Archival Precursor Lesions: Deleted in Malignant Brain Tumors 1 and Tissue Transglutaminase 2 Are Upregulated in Pancreatic Cancer Precursors
Figshare·2017Open Access
Quantification of Anaplastic Lymphoma Kinase Protein Expression in Non–Small Cell Lung Cancer Tissues from Patients Treated with Crizotinib
Clinical Chemistry·2015· 11 citedOpen Access
Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH
Gastric Cancer·2015· 43 citedOpen Access
Abstract 3397: A novel clinical tool that provides quantitative and accurate measurement of Met protein
Cancer Research·2015
Her2 expression in gastroesophageal cancer (GEC) FFPE tissue using mass spectrometry (MS) and correlation with <i>HER2</i> gene amplification.
Journal of Clinical Oncology·2015
Application of tissue mesodissection to molecular cancer diagnostics
Journal of Clinical Pathology·2014· 5 citedOpen Access
537 Absolute quantitation of MET using mass spectrometry for clinical application: assay precision, stability, and correlation with MET gene amplification in FFPE tumor tissue
European Journal of Cancer·2014· 2 citedOpen Access
Absolute Quantitation of Met Using Mass Spectrometry for Clinical Application: Assay Precision, Stability, and Correlation with MET Gene Amplification in FFPE Tumor Tissue
PLoS ONE·2014· 54 citedOpen Access
Quantification of HER2 from gastroesophageal cancer (GEC) FFPE tissue by mass spectrometry (MS).
Journal of Clinical Oncology·2014· 2 cited
Development and clinical validation of an adeno/squamous multiplexed diagnostic assay for NSCLC.
Journal of Clinical Oncology·2013
Application of Selected Reaction Monitoring for Multiplex Quantification of Clinically Validated Biomarkers in Formalin-Fixed, Paraffin-Embedded Tumor Tissue
Journal of Molecular Diagnostics·2013· 64 citedOpen Access
Use of Formalin-Fixed, Paraffin-Embedded Tissue for Proteomic Biomarker Discovery
Methods in molecular biology·2013· 7 cited
Abstract P6-07-17: Proteomic screening of FFPE tissue identifies FKBP4 as an independent prognostic factor in hormone receptor positive breast cancers
Cancer Research·2012· 2 cited
Multiplexed mass spectometic quantitation of HER1-3, cMET, and IGF1R in FFPE tumor samples: Implications for targeted therapy and resistance.
Journal of Clinical Oncology·2012
Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue
Clinical Proteomics·2012· 67 citedOpen Access
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Frequent Co-authors

Michael R. Emmert‐Buck(12), Lance A. Liotta(9), Marlene Darfler(9), Vladimir Knežević(6), Vinay V. Prabhu(6), Peter J. Munson(6), Jon Burrows(6), W. Marston Linehan(5), J. Silvio Gutkind(5), Bradley R. Ringeisen(5), Brian L. Hood(5), Thomas P. Conrads(5), Todd Hembrough(5), Sheeno Thyparambil(5), John W. Gillespie(4), Chidchanok Leethanakul(4), Timothy D. Veenstra(4), Kathleen Bengali(4), Michael A. Tainsky(4), Rodrigo Chuaqui(3)