Thais M. Sielecki

Penn Center for AIDS Research — United States

Immunology and Microbiology · Life Sciences

20h-index1.5kcitations47works0.02yr avg
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Research Topics

Macrophage Migration Inhibitory Factor(10), Nuclear Receptors and Signaling(9), Monoclonal and Polyclonal Antibodies Research(6), Antiplatelet Therapy and Cardiovascular Diseases(5), Cancer-related Molecular Pathways(4)

Publications47 total

Effects of space radiation on the endovasculature: implications for future human deep space exploration
Elsevier eBooks·2021
List of contributors
Elsevier eBooks·2021
Antioxidant Gene Expression in Airway Smooth Muscle and Epithelial Cells is Upregulated by Synthetic Secoisolaricesinol Diglucoside (LGM2605)
Journal of Allergy and Clinical Immunology·2020Open Access
Ozone-induced enhancement of airway hyperreactivity in rhesus macaques: Effects of antioxidant treatment
Journal of Allergy and Clinical Immunology·2019· 21 citedOpen Access
LGM2605 Reduces Inflammatory Phenotype of the Pulmonary Vasculature Following Ischemia/Reperfusion Using an Ex Vivo Mouse Lung Perfusion System
2019
MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential
Nature Reviews Urology·2019· 128 cited
Protective effect of LGM2605 on ozone-induced airway inflammation and hyperreactivity in rhesus macaques
Journal of Allergy and Clinical Immunology·2019Open Access
LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks
International Journal of Molecular Sciences·2019· 23 citedOpen Access
Synthetic Lignan Secoisolariciresinol Diglucoside Reduces Cerebral Leukocyte Mobilization after Traumatic Brain Injury
Journal of the American College of Surgeons·2018
MIF Antagonist (CPSI-1306) Protects against UVB-Induced Squamous Cell Carcinoma
Molecular Cancer Research·2014· 27 citedOpen Access
Macrophage migratory inhibitory factor promotes bladder cancer progression via increasing proliferation and angiogenesis
Carcinogenesis·2013· 63 citedOpen Access
The novel orally active guanylhydrazone CPSI-2364 prevents postoperative ileus in mice independently of anti-inflammatory vagus nerve signaling
Langenbeck s Archives of Surgery·2012· 13 cited
Synthesis and structure–activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2012· 6 citedOpen Access
Abstract 159: Macrophage Migration Inhibitory Factor (MIF) enhances proliferation and expression of tumorigenic cytokines in a bladder cancer cell line
Cancer Research·2012
A small‐molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease
The FASEB Journal·2010· 46 citedOpen Access
Abstract 1549: Oral inhibitors of macrophage migratory inhibitory factor (MIF) lead to reduced tumor burden in a murine model of invasive bladder cancer
Cancer Research·2010
1145 ORAL INHIBITORS OF MACROPHAGE MIGRATORY INHIBITORY FACTOR (MIF) LEAD TO REDUCED TUMOR STAGE AND BURDEN IN A MURINE MODEL OF INVASIVE BLADDER CANCER
The Journal of Urology·2010
Macrophage migration inhibitory factor is a therapeutic target in treatment of non‐insulin‐dependent diabetes mellitus
The FASEB Journal·2010· 61 cited
A critical mediator of leukocyte extravasation during inflammatory disease (50.8)
The Journal of Immunology·2009
Inhibition of p38 Mitogen-Activated Protein Kinase Pathway as Prophylaxis of Postoperative Ileus in Mice
Gastroenterology·2008· 71 citedOpen Access
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Frequent Co-authors

John Wityak(11), Shaker A. Mousa(11), Richard E. Olson(11), Ruth R. Wexler(10), Melpo Christofidou‐Solomidou(8), James R. Pruitt(7), Martin Thoolen(6), A. I. MEYERS(6), Pamela A. Benfield(5), George L. Trainor(5), Donald Pinto(5), John F. Boylan(4), John A. Taylor(4), George Emmett(4), Jean Y. Sze(4), Adrienne L. Racanelli(4), Thomas M. Reilly(4), Shilpa Choudhary(4), Carol C. Pilbeam(4), Caroline C. Whitacre(4)