Donald Pinto

Bristol-Myers Squibb (United States) — United States

Medicine · Health Sciences

34h-index4.7kcitations119works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Blood Coagulation and Thrombosis Mechanisms(28), Atrial Fibrillation Management and Outcomes(21), Coagulation, Bradykinin, Polyphosphates, and Angioedema(17), Venous Thromboembolism Diagnosis and Management(15), Vitamin K Research Studies(11)

Publications119 total

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
Journal of Medicinal Chemistry·2021· 93 citedOpen Access
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups
Journal of Medicinal Chemistry·2019· 22 cited
Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability
Bioorganic & Medicinal Chemistry Letters·2019· 12 citedOpen Access
Faculty Opinions recommendation of Olefin Amine (OLA) Reagents for the Synthesis of Bridged Bicyclic and Spirocyclic Saturated N-Heterocycles by Catalytic HAT Reactions.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Practical and regioselective amination of arenes using alkyl amines.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Abstract 11051: A Small-Molecule Factor XIa Inhibitor (BMS-962212) Provides Robust Antithrombotic Activity in Non-Human Primate Model of Arterial Thrombosis With Low Bleeding
Circulation·2018
Factor XIa Inhibitors as New Anticoagulants
Journal of Medicinal Chemistry·2018· 51 citedOpen Access
CCDC 1568523: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
Journal of Medicinal Chemistry·2017· 51 citedOpen Access
Abstract TMP117: Preclinical and Early Clinical Characterization of a Parenterally Administered Direct Factor XIa Inhibitor
Stroke·2017· 5 cited
Faculty Opinions recommendation of Bioorthogonal Diversification of Peptides through Selective Ruthenium(II)-Catalyzed C-H Activation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of A Mild and Ligand-Free Ni-Catalyzed Silylation via C-OMe Cleavage.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Fe-Catalyzed C-C Bond Construction from Olefins via Radicals.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Photoredox activation of carbon dioxide for amino acid synthesis in continuous flow.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017Open Access
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
Journal of Medicinal Chemistry·2017· 38 citedOpen Access
Faculty Opinions recommendation of Difluoromethyl bioisostere: examining the "lipophilic hydrogen bond donor" concept.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Lewis Acid-Base Interaction-Controlled ortho-Selective C-H Borylation of Aryl Sulfides.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
Bioorganic & Medicinal Chemistry·2016· 22 citedOpen Access
page 1 of 6Next →

Frequent Co-authors

Ruth R. Wexler(30), Joseph M. Luettgen(25), Robert M. Knabb(23), Pancras C. Wong(21), Patrick Y. S. Lam(20), Michael J. Orwat(17), Karen A. Rossi(14), Mimi L. Quan(12), Kan He(11), Alan R. Rendina(9), Richard Alexander(7), James R. Corte(7), Jeffrey M. Bozarth(7), Dietmar Seiffert(7), Angela Smallwood(6), Baomin Xin(6), Earl J. Crain(6), Shuaige Wang(6), Robert A. Galemmo(6), Tianan Fang(6)