Mimi L. Quan

Hebei Medical University — China

Medicine · Health Sciences

27h-index2.0kcitations63works1.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(36), Coagulation, Bradykinin, Polyphosphates, and Angioedema(27), Atrial Fibrillation Management and Outcomes(11), Protease and Inhibitor Mechanisms(8), Vitamin K Research Studies(8)

Publications63 total

Lauric Acid Promotes Esophageal Squamous Cell Carcinoma via GPR84: Lipid Metabolic Dysregulation as a Therapeutic Target
Nutrition and Cancer·2025
Quantitative characterization of cellular morphology of turbulent hydrogen-air spherically expanding flames
International Journal of Hydrogen Energy·2025· 2 cited
Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors
Bioorganic & Medicinal Chemistry Letters·2023· 4 citedOpen Access
Improved efficacy/safety profile of factor XIa inhibitor BMS‐724296 versus factor Xa inhibitor apixaban and thrombin inhibitor dabigatran in cynomolgus monkeys
Research and Practice in Thrombosis and Haemostasis·2021· 7 citedOpen Access
Anticoagulants
Burger's Medicinal Chemistry and Drug Discovery·2021
Identification of 5H-chromeno[3,4-c]pyridine and 6H-isochromeno[3,4-c]pyridine derivatives as potent and selective dual ROCK inhibitors
Bioorganic & Medicinal Chemistry Letters·2020· 15 citedOpen Access
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Bioorganic & Medicinal Chemistry Letters·2020· 11 citedOpen Access
Factor XIa Inhibitors as New Anticoagulants
Journal of Medicinal Chemistry·2018· 51 citedOpen Access
Pyridazine and pyridazinone derivatives as potent and selective factor XIa inhibitors
Bioorganic & Medicinal Chemistry Letters·2018· 21 citedOpen Access
CCDC 1568523: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
Journal of Medicinal Chemistry·2017· 51 citedOpen Access
Macrocyclic factor XIa inhibitors
Bioorganic & Medicinal Chemistry Letters·2017· 10 citedOpen Access
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
Bioorganic & Medicinal Chemistry Letters·2017· 19 citedOpen Access
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
Journal of Medicinal Chemistry·2017· 38 citedOpen Access
Advances in Anticoagulants
Elsevier eBooks·2016· 3 cited
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
Bioorganic & Medicinal Chemistry·2016· 22 citedOpen Access
Novel phenylalanine derived diamides as Factor XIa inhibitors
Bioorganic & Medicinal Chemistry Letters·2015· 28 citedOpen Access
In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa
Journal of Thrombosis and Thrombolysis·2015· 38 cited
Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1<i>H</i>)-one as the P2′ Moiety
ACS Medicinal Chemistry Letters·2015· 26 citedOpen Access
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties
Bioorganic & Medicinal Chemistry Letters·2015· 40 citedOpen Access
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Frequent Co-authors

Ruth R. Wexler(42), Joseph M. Luettgen(26), Pancras C. Wong(25), Robert M. Knabb(21), Karen A. Rossi(20), Patrick Y. S. Lam(16), Dietmar Seiffert(15), Donald Pinto(13), Jeffrey M. Bozarth(12), Christopher D. Ellis(11), Alan R. Rendina(11), Cailan Wang(9), Joseph E. Myers(9), S. Sheriff(9), Richard Alexander(8), Carol A. Watson(8), Earl J. Crain(8), James R. Corte(8), Michael J. Orwat(7), Joanne M. Smallheer(7)