Jianjun Wu

Cleveland Clinic Lerner College of Medicine — United States

Immunology and Microbiology · Life Sciences

18h-index2.2kcitations30works12.02yr avg
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Research Topics

interferon and immune responses(11), Viral Infections and Vectors(7), Cytomegalovirus and herpesvirus research(6), Inflammasome and immune disorders(5), Hepatocellular Carcinoma Treatment and Prognosis(4)

Publications30 total

STT3A-mediated mega protein complex assembly during dengue and Zika virus infection
iScience·2025Open Access
STING trafficking activates MAPK–CREB signaling to trigger regulatory T cell differentiation
Proceedings of the National Academy of Sciences·2024· 24 citedOpen Access
CTRP13 Mitigates Endothelial Cell Ferroptosis via the AMPK/KLF4 Pathway: Implications for Atherosclerosis Protection
Medical Science Monitor·2023· 3 citedOpen Access
C1q/tumor necrosis factor-related protein 13 attenuated endothelial cell ferroptosis by the AMPK/KLF4 pathway
Research Square (Research Square)·2023Open Access
A rare presentation of lung squamous cell carcinoma metastasis to the distal phalanx of the little finger: a case report
Cancer Innovation·2022· 1 citedOpen Access
No Longer A One-Trick Pony: STING Signaling Activity Beyond Interferon
Journal of Molecular Biology·2021· 22 citedOpen Access
Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS
Nucleic Acids Research·2021· 48 citedOpen Access
Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
Nature·2021· 214 citedOpen Access
A “KU” new sensor for cytosolic DNA in T cells
Immunity·2021· 3 citedOpen Access
Heat shock enhances outer-membrane vesicle release in Bordetella spp.
Current Research in Microbial Sciences·2020· 35 citedOpen Access
Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion
Immunity·2020· 348 citedOpen Access
Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP
Nature Immunology·2020· 127 citedOpen Access
STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
The Journal of Experimental Medicine·2019· 303 citedOpen Access
STIM1 moonlights as an anchor for STING
Nature Immunology·2019· 16 cited
Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response
Cell Reports·2017· 302 citedOpen Access
STING-associated vasculopathy develops independently of IRF3 in mice
The Journal of Experimental Medicine·2017· 199 citedOpen Access
Kaposi's Sarcoma-Associated Herpesvirus Inhibitor of cGAS (KicGAS), Encoded by ORF52, Is an Abundant Tegument Protein and Is Required for Production of Infectious Progeny Viruses
Journal of Virology·2016· 55 citedOpen Access
[Advances in the research of biological characters and pathophysiological effects of dendritic epidermal T lymphocytes].
PubMed·2016
ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and Are Required for Optimal Production of Infectious Progeny Viruses
Journal of Virology·2015· 27 citedOpen Access
Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
Cell Host & Microbe·2015· 274 citedOpen Access
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Frequent Co-authors

Nan Yan(9), Wenwei Li(5), Fanxiu Zhu(5), Nicole Dobbs(4), Kun Yang(4), Denis Avey(4), Teh‐Ia Huo(4), Yi‐Hsiang Huang(4), P.‐C. Lee(4), S.‐D. Lee(4), Tomomi Sakai(3), Joseph Gillen(3), Siming Ma(3), J.‐H. Chiang(3), F.‐Y. Chang(3), Fan Yang(3), Jonathan J. Miner(2), Vijay K. Gonugunta(2), Vladislav Pokatayev(2), Wendell Miley(2)