Loan Miller

Lake County — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index1.1kcitations32works0.72yr avg
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Research Topics

Receptor Mechanisms and Signaling(11), Neurotransmitter Receptor Influence on Behavior(7), Pharmacological Receptor Mechanisms and Effects(6), Neuroscience and Neuropharmacology Research(4), Pain Mechanisms and Treatments(4)

Publications32 total

NGN2 Expression and Regional Patterning Allow Rapid Differentiation from hiPSCs to DRG-Like Neurons Responsive to Type 2 Cytokines
2025Open Access
BMP, MEK, and WNT inhibition with NGN2 expression for rapid generation of hiPSC-derived neurons amenable to regional patterning
Stem Cell Reports·2025· 2 citedOpen Access
Induction of Human Pruriceptors from Pluripotent Stem Cells via Transcription Factors
2025Open Access
Cytokine induced 3‐D organotypic psoriasis skin model demonstrates distinct roles for NF‐κB and JAK pathways in disease pathophysiology
Experimental Dermatology·2022· 15 citedOpen Access
Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes
Transplantation·2019· 20 citedOpen Access
Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation
Clinical Transplantation·2019· 12 cited
Implementation of a human podocyte injury model of chronic kidney disease for profiling of renoprotective compounds
European Journal of Pharmacology·2017· 8 cited
Macrophages play a pathogenic role in IL-23 mediated psoriasiform skin inflammation
The Journal of Immunology·2017· 3 cited
677 Human skin biopsy culture model maintains psoriasis disease features and demonstrates Pathway Engagement by Dexamethasone
Journal of Investigative Dermatology·2017
Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain
Bioorganic & Medicinal Chemistry Letters·2013· 8 citedOpen Access
Default-Mode-Like Network Activation in Awake Rodents
PLoS ONE·2011· 98 citedOpen Access
Indol-3-yl-tetramethylcyclopropyl Ketones: Effects of Indole Ring Substitution on CB<sub>2</sub> Cannabinoid Receptor Activity
Journal of Medicinal Chemistry·2008· 77 citedOpen Access
Discovery of 3-Methyl-<i>N</i>-(1-oxy-3‘,4‘,5‘,6‘-tetrahydro-2‘<i>H</i>-[2,4‘-bipyridine]-1‘-ylmethyl)benzamide (ABT-670), an Orally Bioavailable Dopamine D<sub>4</sub> Agonist for the Treatment of Erectile Dysfunction
Journal of Medicinal Chemistry·2006· 43 citedOpen Access
Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist
British Journal of Pharmacology·2006· 50 citedOpen Access
1-Aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one Oximes as Potent Dopamine D<sub>4</sub>Receptor Agonists for the Treatment of Erectile Dysfunction
Journal of Medicinal Chemistry·2006· 19 citedOpen Access
Correlation between brain/plasma ratios and efficacy in neuropathic pain models of selective metabotropic glutamate receptor 1 antagonists
Bioorganic & Medicinal Chemistry Letters·2006· 21 citedOpen Access
Acrylamide Analog as a Novel Nitric Oxide-Independent Soluble Guanylyl Cyclase Activator
Journal of Pharmacological Sciences·2006· 15 citedOpen Access
Structure−Activity Relationship of Triazafluorenone Derivatives as Potent and Selective mGluR1 Antagonists
Journal of Medicinal Chemistry·2005· 71 citedOpen Access
Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists
Bioorganic & Medicinal Chemistry·2005· 32 cited
2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist
Neuropharmacology·2005· 16 cited
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Frequent Co-authors

Masaki Nakane(15), Robert B. Moreland(15), Jorge D. Brioni(15), Renjie Chang(11), Marie E. Uchic(11), Andrew O. Stewart(11), Marc A. Terranova(9), Gin C. Hsieh(8), Diana L. Donnelly‐Roberts(8), Marian T. Namovic(8), Pramila Bhatia(6), Teodozyj Kolasa(6), Teodozyi Kolasa(6), Mark A. Matulenko(6), Kennan C. Marsh(6), Meena Patel(5), Prisca Honoré(5), Jill M. Wetter(5), Victoria Scott(5), Odile F. El-Kouhen(4)