Norbert Lehming

National University of Singapore — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.7kcitations50works17.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(13), Ubiquitin and proteasome pathways(13), Fungal and yeast genetics research(11), RNA and protein synthesis mechanisms(9), Bacterial Genetics and Biotechnology(7)

Publications50 total

Mitochondria and the Repurposing of Diabetes Drugs for Off-Label Health Benefits
International Journal of Molecular Sciences·2025· 17 citedOpen Access
Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins
Cells·2023· 12 citedOpen Access
Systematic Approaches To Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins
Preprints.org·2023· 1 citedOpen Access
Ubiquitination Occurs in the Mitochondrial Matrix by Eclipsed Targeted Components of the Ubiquitination Machinery
Cells·2022· 15 citedOpen Access
Author Reply to Peer Reviews of Ubiquitination occurs in the mitochondrial matrix by eclipsed components of the ubiquitin machinery
2022· 4 cited
Ubiquitination occurs in the mitochondrial matrix by eclipsed targeted components of the ubiquitin machinery
2022· 1 citedOpen Access
Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation
iScience·2021· 9 citedOpen Access
A combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in <i>Escherichia coli</i>
Proceedings of the National Academy of Sciences·2021· 16 citedOpen Access
Post-translational Modifications of Fumarase Regulate its Enzyme Activity and Function in Respiration and the DNA Damage Response
Journal of Molecular Biology·2020· 10 citedOpen Access
A novel combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in <i>E. coli</i>
2020Open Access
Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2
2020
Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression
Frontiers in Molecular Biosciences·2018· 58 citedOpen Access
Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2
Current Genetics·2017· 29 cited
Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism
Traffic·2016· 39 citedOpen Access
Differential Regulation of Proinflammatory Cytokine Expression by Mitogen-Activated Protein Kinases in Macrophages in Response to Intestinal Parasite Infection
Infection and Immunity·2014· 90 citedOpen Access
How the ubiquitin proteasome system regulates the regulators of transcription
Transcription·2012· 10 citedOpen Access
Mediator Acts Upstream of the Transcriptional Activator Gal4
PLoS Biology·2012· 13 citedOpen Access
Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite
The International Journal of Biochemistry & Cell Biology·2011· 18 cited
The histone variant H2A.Z interconverts two stable epigenetic chromatin states
Biochemical Journal·2011
Galactose induction of the <i>GAL1</i> gene requires conditional degradation of the Mig2 repressor
Biochemical Journal·2011· 17 cited
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Frequent Co-authors

Ophry Pines(13), B. von Wilcken‐Bergmann(8), Benno Müller‐Hill(7), Koyeli Das(7), Jutta Schüller(6), Mark Ptashne(5), J. Sartorius(5), Brigitte Kisters–Woike(5), Christine Bongards(4), Wee Leng Siew(4), Yu Zhang(4), Ofri Karmon(4), Joshua M. Brickman(3), Michael Leshets(3), Yardena Silas(3), Jürgen Sartorius(3), Dharanidharan Ramamurthy(3), Boon Shang Chew(3), Joyce Yip(3), Maayan Mark(3)