Joshua M. Brickman

Novo Nordisk Foundation — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index5.8kcitations136works4.92yr avg
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Research Topics

Pluripotent Stem Cells Research(68), CRISPR and Genetic Engineering(38), 3D Printing in Biomedical Research(18), Renal and related cancers(18), Single-cell and spatial transcriptomics(13)

Publications136 total

Post-replicative chromatin accessibility predicts cell fate change
Stem Cell Reports·2026Open Access
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Nature Communications·2025· 2 citedOpen Access
Cell-context response to germ layer differentiation signals is predetermined by the epigenome in regionalized epiblast populations
Nature Communications·2025· 2 citedOpen Access
Differential Elasticity Affects Lineage Segregation of Embryonic Stem Cells
Physical Review Letters·2025· 4 cited
Altering metabolism programs cell identity via NAD+-dependent deacetylation
The EMBO Journal·2025· 1 citedOpen Access
PRC2 promotes canalisation during endodermal differentiation
PLoS Genetics·2025· 3 citedOpen Access
A bipartite function of ESRRB can integrate signalling over time to balance self - renewal and differentiation
Zenodo (CERN European Organization for Nuclear Research)·2025Open Access
A Deep Learning Approach to Assessing Cell Identity in Stem Cell–Based Embryo Models
Methods in molecular biology·2025· 2 cited
nf-core/marsseq: systematic preprocessing pipeline for MARS-seq experiments
Bioinformatics Advances·2024· 3 citedOpen Access
nf-core/marsseq: systematic pre-processing pipeline for MARS-seq experiments
Zenodo (CERN European Organization for Nuclear Research)·2024Open Access
Cells transit through a quiescent-like state to convert to neurons at high rates
2024· 2 citedOpen Access
Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing
Nature Methods·2024· 16 citedOpen Access
Common modes of ERK induction resolve into context-specific signalling via emergent networks and cell-type-specific transcriptional repression
Development·2024· 3 citedOpen Access
Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion
Cell stem cell·2024· 11 citedOpen Access
Author Reply to Peer Reviews of PRC2 Promotes Canalisation During Endodermal Differentiation
2024
The primitive endoderm supports lineage plasticity to enable regulative development
Cell·2024· 27 citedOpen Access
PRC2 Promotes Canalisation During Endodermal Differentiation
2024· 1 citedOpen Access
Common modes of ERK induction resolve into context specific signalling via a combination of signal duration and cell type specific transcriptional repression
2024Open Access
Deep Learning Based Models for Preimplantation Mouse and Human Development
2024· 2 citedOpen Access
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
2024· 11 citedOpen Access
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Frequent Co-authors

William B. Hamilton(5), Maurice A. Canham(5), Sophie M. Morgani(5), Mark Ptashne(5), Mehul Dattani(4), Rosa Beddington(4), Alexei A. Sharov(4), Minoru S.H. Ko(4), Alessandra Livigni(4), Rajeev Gupta(3), J K Wales(3), Jennifer Nichols(3), Rosa Portero Migueles(3), Norbert Lehming(3), Gillian Morrison(3), Rita S. Monteiro(3), Ala Trusina(3), Alba Redó Riveiro(3), Juan Pedro Martı́nez-Barberá(2), Paul Q. Thomas(2)