Roddy S. O’Connor

California University of Pennsylvania — United States

Medicine · Health Sciences

33h-index11.4kcitations144works3.82yr avg
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Research Topics

CAR-T cell therapy research(67), Immune Cell Function and Interaction(54), Viral Infectious Diseases and Gene Expression in Insects(18), T-cell and B-cell Immunology(16), Immunotherapy and Immune Responses(16)

Publications144 total

FcεRγI promotes canine CD8 chimeric antigen receptor T cell cytotoxicity through a Syk-NF-κB axis
Molecular Therapy·2025Open Access
Supplementary Figure 1 from Current Status and Challenges of Vaccination Therapy for Glioblastoma
2025Open Access
Supplementary Figure 7 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 4 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 1 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 2 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 5 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 3 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Table 1 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Supplementary Figure 6 from Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
2025Open Access
Monocarboxylate transporter 1 deficient donor T cells rewire metabolism and ameliorate aGVHD lethality
Blood·2025Open Access
Single-day non-activated IL-18-armed CAR T cells with enhanced persistence and durable efficacy
Blood·2025Open Access
Metabolic conditioning for enhanced CAR T cell function
Blood·2025
Glucose transporter 5 enhances CAR-T cell metabolic function and serial killing
Blood·2025
1337 Gut-targeted antibiotic modulation enhances radiotherapy in NSCLC: New epigenetic and dendritic cell functional correlates from a randomized pilot trial
2025Open Access
Lipids in ovarian cancer ascites impair T cell function by disrupting TCR dynamics 9157
The Journal of Immunology·2025Open Access
Distinct glutamine metabolic pathways support mitochondrial function in canine T cells 4008
The Journal of Immunology·2025Open Access
Piezo1-mediated mechano-energetics regulate CAR T cell function
2025· 1 citedOpen Access
Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion
Journal of Clinical Investigation·2025· 1 citedOpen Access
T cell InaDAGquacy in the TME driven by phosphoethanolamine
Developmental Cell·2025
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Frequent Co-authors

Michael C. Milone(19), Carl H. June(16), Saba Ghassemi(9), Nathaniel W. Snyder(7), Selene Nuñez-Cruz(6), John Leferovich(6), Joseph A. Fraietta(5), Bruce L. Levine(5), J. Joseph Melenhorst(5), Grace K. Pavlath(5), Simon F. Lacey(4), Regina M. Young(4), Saar Gill(4), John Scholler(4), Sophie Trefely(4), Bruce R. Blazar(4), Andre Kelly(4), Stefan Lundh(3), Changfeng Zhang(3), Felipe Bedoya(3)