Lorenz M. Urner

UCLA Health — United States

Materials Science · Physical Sciences

7h-index235citations38works0.52yr avg
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Research Topics

Crystallization and Solubility Studies(23), X-ray Diffraction in Crystallography(21), Glioma Diagnosis and Treatment(3), Porphyrin and Phthalocyanine Chemistry(3), Photochemistry and Electron Transfer Studies(3)

Publications38 total

DDDR-43. ERAS-801 IS A SELECTIVE BRAIN-PENETRANT EGFR INHIBITOR WITH IMPROVED ACTIVITY AGAINST EGFR EXTRACELLULAR DOMAIN-MUTANT GLIOBLASTOMA
Neuro-Oncology·2024· 1 citedOpen Access
134 (PB122): ERAS-801: a selective brain-penetrant EGFR inhibitor with improved activity against EGFR extracellular domain-mutant glioblastoma
European Journal of Cancer·2024
Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein–Protein Interaction Modulator with the Potential of Treating Hematological Malignancies
Journal of Medicinal Chemistry·2023· 23 cited
CCDC 2103287: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103281: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103286: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103283: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103284: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103282: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 2103285: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Intramolecular N−H⋅⋅⋅F Hydrogen Bonding Interaction in a Series of 4‐Anilino‐5‐Fluoroquinazolines: Experimental and Theoretical Characterization of Electronic and Conformational Effects
Chemistry - A European Journal·2021· 16 citedOpen Access
Nocturnal cerebral tissue oxygenation in lowlanders with chronic obstructive pulmonary disease travelling to an altitude of 2,590 m: Data from a randomised trial
Journal of Sleep Research·2021· 7 cited
CCDC 1913485: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1913486: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors
ACS Medicinal Chemistry Letters·2020· 32 citedOpen Access
DDIS-17. DEVELOPMENT OF BRAIN-PENETRANT EGFR INHIBITORS FOR CNS MALIGNANCIES
Neuro-Oncology·2019· 2 citedOpen Access
Automatic Processing of Nasal Pressure Recordings to Derive Continuous Side-Selective Nasal Airflow and Conductance
Frontiers in Physiology·2019· 4 citedOpen Access
DDIS-08. DEVELOPMENT OF BRAIN-PENETRANT EGFR INHIBITORS FOR GLIOBLASTOMA
Neuro-Oncology·2018Open Access
Porphyrin Donor and Tunable Push–Pull Acceptor Conjugates—Experimental Investigation of Marcus Theory
Chemistry - A European Journal·2017· 28 cited
CCDC 1431981: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
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Frequent Co-authors

Jean‐Paul Gisselbrecht(17), Corinne Boudon(17), François Diederich(17), Michael Sekita(16), Nils Trapp(16), Dirk M. Guldi(16), Michael E. Jung(15), W. Bernd Schweizer(14), Michael Wörle(13), Ga Young Lee(8), Joseph W. Treacy(8), Aneta Turlik(8), Saeed I. Khan(8), K. N. Houk(8), Timothy F. Cloughesy(7), Jonathan Tsang(5), Peter M. Clark(5), David A. Nathanson(5), Gyudong Kim(4), Kingsley Chow(4)