Joseph Rosenbluh

Australian Regenerative Medicine Institute — Australia

Medicine · Health Sciences

28h-index4.7kcitations106works2.12yr avg
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Research Topics

Acute Myeloid Leukemia Research(23), CRISPR and Genetic Engineering(20), RNA modifications and cancer(17), RNA Research and Splicing(14), NF-κB Signaling Pathways(12)

Publications106 total

De novo design of potent CRISPR–Cas13 inhibitors
Nature Chemical Biology·2026· 1 citedOpen Access
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease
Nature Neuroscience·2025· 1 citedOpen Access
Structures of tRNA-bound CRISPR-Cas13 reveal universal HEPN RNase mechanisms
2025· 1 cited
A basic framework to explain splice-site choice in eukaryotes
Nature Communications·2025· 1 citedOpen Access
Generation of two Betacellulin CRISPR-Cas9 knockout hiPSC lines to study the affected EGF system paradigm in schizophrenia
Stem Cell Research·2025Open Access
The design and synthesis of a novel α-alkynylated biotin scaffold for use in heterobifunctional molecular probes
Tetrahedron Letters·2025Open Access
Single-cell Pharmacogenomic Landscapes of Epigenetic Drug Resistance Revealed by Gastric Cancer Perturb-seq
2025Open Access
<i>SRP19</i> and the protein secretion machinery is a targetable vulnerability in cancers with <i>APC</i> loss
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
“Generation of two Betacellulin CRISPR-Cas9 knockout hiPSC lines to study affected EGF system paradigm in Schizophrenia”
2025Open Access
The Design and Synthesis of a Novel A-Alkynylated Biotin Scaffold for Use in Heterobifunctional Molecular Probes
SSRN Electronic Journal·2025Open Access
SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers
Nature Communications·2024Open Access
Abstract B003: Systematic loss-of-function screens identify pathway-specific functional circular RNAs
Molecular Cancer Therapeutics·2024
Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
EMBO Reports·2024· 8 citedOpen Access
Systematic loss-of-function screens identify pathway-specific functional circular RNAs
Nature Cell Biology·2024· 4 cited
CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair
Molecular Cancer·2024· 21 citedOpen Access
Pooled genetic screens identify breast cancer risk genes involved in evasion from T cell-mediated killing
2024Open Access
A basic framework governing splice-site choice in eukaryotes
2024· 1 citedOpen Access
<i>SRP19</i> and the protein secretion machinery is a targetable vulnerability in cancers with <i>APC</i> loss
2024· 1 citedOpen Access
SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers
2024Open Access
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies
Genome biology·2023· 20 citedOpen Access
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Frequent Co-authors

William C. Hahn(14), Abraham Loyter(13), Aviad Tsherniak(8), Jill P. Mesirov(8), Barbara A. Weir(7), David E. Root(7), Rameen Beroukhim(6), Deepak Nijhawan(5), Travis Zack(5), Xiaoxing Wang(5), Steven E. Schumacher(5), Francisca Vázquez(5), Aviad Levin(5), A. Graessmann(5), Pablo Tamayo(5), Natasha Tuano(5), Anna C. Schinzel(4), Diane D. Shao(4), Glenn S. Cowley(4), Zvi Hayouka(4)