William C. Hahn

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

146h-index100.6kcitations1.1kworks9.32yr avg
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Research Topics

Cancer Genomics and Diagnostics(187), Ubiquitin and proteasome pathways(76), Cancer-related gene regulation(69), Prostate Cancer Treatment and Research(66), Protein Degradation and Inhibitors(66)

Publications1.1k total

Supplementary Figures and Tables from A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas
2025Open Access
Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
2025Open Access
Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
2025Open Access
Ammonolysis Under NH <sub>3</sub> –Limiting Conditions as a Pathway to Improved LaTiO <sub>2</sub> N Water Splitting Photoanodes
ACS Applied Energy Materials·2025· 3 cited
Dopant diffusion and segregation of iron in a near 45° (100) twist grain boundary in SrTiO <sub>3</sub>
Journal of the American Ceramic Society·2025· 1 citedOpen Access
Abstract B019: O-mannosylation represents a therapeutic opportunity in BRAF fusion protein oncogenesis
Cancer Research·2025
Abstract A032: Molecular insights into KIAA1549::BRAF fusion proteins: Implications for targeted therapy in pediatric low-grade gliomas
Cancer Research·2025
O-mannosylation and protein maturation check-points represent therapeutic opportunities in BRAF fusion protein oncogenesis
2025Open Access
A neomorphic protein interface catalyzes covalent inhibition of RAS <sup>G12D</sup> aspartic acid in tumors
Science·2025· 18 cited
Clinical response to novel combination of trastuzumab deruxtecan and abiraterone in HER2-expressing metastatic castration-resistant prostate cancer
The Oncologist·2025Open Access
Iron Enrichment at Grain Boundaries in SrTiO3: Does It Stay or Does It Go?
Microscopy and Microanalysis·2025Open Access
RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
UNC Libraries·2025Open Access
CREB5 promotes immunotherapy resistance via tumor-intrinsic collagen matrix deposition
2025Open Access
Abstract LB318: MYC primes a paralog synthetic lethality involving the mitochondrial transporters TIMM17A and TIMM17B and N-acetylaspartate
Cancer Research·2025
Abstract 986: <i>SMARCB1</i> missense mutants destabilize SWI/SNF complex stability and remodeling activity
Cancer Research·2025
Cancer Dependency Map: Past and Present
Annual Review of Cancer Biology·2025Open Access
SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity
2025· 1 citedOpen Access
Electric field‐induced defect redistribution along a near 23° (100) tilt grain boundary in SrTiO <sub>3</sub>
Journal of the American Ceramic Society·2025· 1 citedOpen Access
Author Correction: An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA
Nature·2025Open Access
A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
Nature Communications·2025· 11 citedOpen Access
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Frequent Co-authors

David E. Root(17), Matthew Meyerson(14), Jesse S. Boehm(13), Levi A. Garraway(11), Barbara A. Weir(10), Todd R. Golub(10), Robert A. Weinberg(10), So Young Kim(8), Aviad Tsherniak(8), Francisca Vázquez(8), Ian F. Dunn(6), Anna C. Schinzel(6), Eric S. Lander(6), Gad Getz(6), Pablo Tamayo(5), Serena J. Silver(5), David M. Sabatini(5), Gregory V. Kryukov(5), Cory M. Johannessen(5), Glenn S. Cowley(5)