Eric S. Lander

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

270h-index510.3kcitations881works15.22yr avg
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Research Topics

Genomics and Chromatin Dynamics(93), Cancer Genomics and Diagnostics(83), Genetic Associations and Epidemiology(79), RNA and protein synthesis mechanisms(78), Genetic Mapping and Diversity in Plants and Animals(78)

Publications856 total

Abstract B120: Mapping and modulating epithelial-mesenchymal plasticity under RAS(ON) multi-selective inhibition in PDAC through lineage tracing and Perturb-seq
Cancer Research·2025
Affordable, manageable, practical, and scalable (AMPS) high-yield and high-gain inertial fusion
Physics of Plasmas·2025· 9 citedOpen Access
Efficiently quantifying dependence in massive scientific datasets using InterDependence Scores
Proceedings of the National Academy of Sciences·2025Open Access
Rewriting regulatory DNA to dissect and reprogram gene expression
Cell·2025· 15 cited
Affordable, manageable, practical, and scalable (AMPS) high-yield and high-gain inertial fusion
arXiv (Cornell University)·2025Open Access
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
Science·2025· 4 citedOpen Access
Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
2024· 44 citedOpen Access
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
2024· 2 citedOpen Access
Cohesin-mediated 3D contacts tune enhancer-promoter regulation
2024· 27 citedOpen Access
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample
Cell·2024· 26 citedOpen Access
Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits
2024· 27 citedOpen Access
Functional dissection of complex and molecular trait variants at single nucleotide resolution
2024· 26 citedOpen Access
Abstract NG08: Dissecting and quantifying pancreatic cancer plasticity using single-cell multiomics, lineage tracing and functional genomics reveals novel mediators of therapy resistance
Cancer Research·2024
Abstract 6940: The transcriptional and epigenetic regulation of epithelial-mesenchymal plasticity in patient-derived pancreatic cancer cell lines
Cancer Research·2024
Convergence of coronary artery disease genes onto endothelial cell programs
Nature·2024· 86 citedOpen Access
Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever
Nature Microbiology·2024· 7 citedOpen Access
Rewriting regulatory DNA to dissect and reprogram gene expression
2023· 19 citedOpen Access
Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies
Nature Genetics·2023· 38 cited
Data for Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Data for Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies
2023· 1 citedOpen Access
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Frequent Co-authors

Todd R. Golub(12), Jill P. Mesirov(10), Stacey Gabriel(10), Pablo Tamayo(9), Gad Getz(8), B Bernstein(8), Matthew Meyerson(7), David Altshuler(5), Wendy Winckler(5), Michael S. Lawrence(5), Kristian Cibulskis(5), Tarjei S. Mikkelsen(5), Aviv Regev(5), James Robinson(4), Mitchell Guttman(4), Mark J. Daly(4), Neva C. Durand(4), Ido Machol(4), Erez Lieberman Aiden(4), Rudolf Jaenisch(4)