Jesse S. Boehm

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

59h-index41.5kcitations328works1.42yr avg
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Research Topics

Cancer Genomics and Diagnostics(129), Bioinformatics and Genomic Networks(62), Genetics, Bioinformatics, and Biomedical Research(52), CRISPR and Genetic Engineering(30), Ovarian cancer diagnosis and treatment(26)

Publications326 total

Abstract B019: O-mannosylation represents a therapeutic opportunity in BRAF fusion protein oncogenesis
Cancer Research·2025
Abstract A008-PR002: Membrane localization mediated by BRAF fusion partners is necessary for transformation of human neural stem cells
Cancer Research·2025
Abstract A032: Molecular insights into KIAA1549::BRAF fusion proteins: Implications for targeted therapy in pediatric low-grade gliomas
Cancer Research·2025
O-mannosylation and protein maturation check-points represent therapeutic opportunities in BRAF fusion protein oncogenesis
2025Open Access
Abstract 6608: Integrating HCMI models and tumors with CCLE and TCGA: Advancing cancer modeling and precision oncology
Cancer Research·2025
Abstract 6358: Single cell transcriptional dynamics in the HCMI cancer model collection
Cancer Research·2025
Abstract 4005: Integrative clinical and molecular characterization of an international community resource of organoid models of human cancer
Cancer Research·2025
Abstract 3882: Patterns of genomic patient-model conservation and evolution in the Human Cancer Models Initiative (HCMI) next-generation cancer model resource
Cancer Research·2025
Abstract 1165: The landscape of molecular targets across 665 next-generation cancer models in the human cancer models initiative identifies opportunities for improved therapy and overcoming resistance
Cancer Research·2025
Abstract IA007: Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer
Cancer Research·2025
Abstract A001: AscitesPredict: Validating anti-cancer therapeutic efficacy in gastroesophageal cancer using rapid ex vivo high-dimensional morphology profiling
Cancer Research·2025
Abstract B025: Integrative clinical and molecular analysis of 665 next-generation in vitro cancer models generated by the the Human Cancer Models Initiative (HCMI) for advancing precision medicine and functional drug discovery
Cancer Research·2025· 1 cited
Think zebras: challenges and opportunities for treating rare cancers
Trends in cancer·2025
Assist-as-Needed Approach for Upper-Limb Robotic Mirror Therapy
Biosystems & biorobotics·2025
Precision preclinical modeling to advance cancer treatment
JNCI Journal of the National Cancer Institute·2024· 8 citedOpen Access
Supporting Functional Tasks in Bi-Manual Robotic Mirror Therapy by Coupling Upper Limb Movements Based on Virtual Reality
2024· 1 cited
LGG-29. BEYOND MAPK SIGNALING - GENOME-SCALE CRISPR/CAS9 SCREENS REVEAL NEW TARGETS FOR TREATMENT OF KIAA1549::BRAF-DRIVEN PEDIATRIC LOW-GRADE GLIOMA
Neuro-Oncology·2024Open Access
LGG-26. A ROLE FOR BRAF FUSION PARTNERS IN ONCOGENIC SIGNALING
Neuro-Oncology·2024Open Access
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries
Nature Communications·2024· 8 citedOpen Access
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin
Communications Biology·2024· 6 citedOpen Access
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Frequent Co-authors

William C. Hahn(35), Todd R. Golub(25), David E. Root(23), Francisca Vázquez(16), Aviad Tsherniak(15), Barbara A. Weir(14), Matthew Meyerson(14), Gad Getz(13), Pablo Tamayo(12), Levi A. Garraway(10), James M. McFarland(10), John G. Doench(8), Yashaswi Shrestha(8), Jill P. Mesirov(7), Glenn S. Cowley(7), So Young Kim(6), Eric S. Lander(6), Jordi Barretina(6), Michael S. Lawrence(6), Bang Wong(6)