Sheng Tian

Huazhong Agricultural University — China

Computer Science · Physical Sciences

34h-index5.4kcitations111works4.12yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Computational Drug Discovery Methods(24), Receptor Mechanisms and Signaling(11), Adenosine and Purinergic Signaling(8), Protein Structure and Dynamics(7), Synthesis and biological activity(7)

Publications111 total

Discovering Latent Relationship for Temporal Knowledge Graph Reasoning
Lecture notes in computer science·2025
Discovery of Novel P2Y <sub>14</sub> R Inhibitors for Ameliorating Liver Fibrosis by Suppressing Hepatic Stellate Cell Activation
Journal of Medicinal Chemistry·2025
Discovery of New <i>N</i> -H Aporphine Derivatives As Brain-Penetrant G <sub>q</sub> -Biased 5-HT <sub>2C</sub> Receptor Agonists and Dual 5-HT <sub>2C</sub> /5-HT <sub>2A</sub> Receptor Agonists
Journal of Medicinal Chemistry·2025
Allosteric Cooperativity Mechanism Investigation of Orthosteric and Allosteric Ligands in Modulating AR Activity: A Molecular Dynamics Study
Journal of Chemical Information and Modeling·2025· 1 cited
Computational discovery and repurposing of chloramphenicol succinate as a potent P2Y14 receptor antagonist for inflammatory bowel disease therapy
Journal of Advanced Research·2025· 1 citedOpen Access
Discovery and proof-of-concept study of a novel highly selective sigma-1 receptor agonist for antipsychotic drug development
Acta Pharmaceutica Sinica B·2025· 3 citedOpen Access
P2Y <sub>12</sub> R antagonists in antithrombotic therapy: a patent and literature review (2019–present)
Expert Opinion on Therapeutic Patents·2025· 3 cited
Identification of a Novel Substrate for eEF2K and the AURKA‐SOX8 as the Related Pathway in TNBC
Advanced Science·2025· 7 citedOpen Access
Attributes novel drug candidate: Constitutive GPCR signal bias mediated by purinergic receptors
Pharmacology & Therapeutics·2025· 4 cited
Structure–Activity Relationship Studies of Substituted 2-Phenyl-1,2,4-triazine-3,5(2<i>H</i>,4<i>H</i>)-dione Analogues: Development of Potent eEF2K Degraders against Triple-Negative Breast Cancer
Journal of Medicinal Chemistry·2024· 6 citedOpen Access
Prediction of Drug‐Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches
Chemical Biology & Drug Design·2024· 4 citedOpen Access
Recent advances in the development of P2Y <sub>14</sub> R inhibitors: a patent and literature review (2018-present)
Expert Opinion on Therapeutic Patents·2024· 4 cited
Genetic analysis of a family affected by congenital myasthenic syndrome due to a Novel mutation in the SLC5A7 gene
BMC Neurology·2024Open Access
Prediction of Drug-Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches
Research Square (Research Square)·2024Open Access
Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis
Nature Communications·2024· 30 citedOpen Access
Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells
Biomedicine & Pharmacotherapy·2024· 5 citedOpen Access
Subgraph Retrieval Enhanced by Graph-Text Alignment for Commonsense Question Answering
Lecture notes in computer science·2024· 1 citedOpen Access
Identification of Spiro[chromene-2,4′-piperidine]s as Potent, Selective, and G<sub>q</sub>-Biased 5-HT<sub>2C</sub> Receptor Partial Agonists
ACS Medicinal Chemistry Letters·2023· 2 citedOpen Access
Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple‐Negative Breast Cancer
Advanced Science·2023· 19 citedOpen Access
Extraction and Analysis of Lipid Raft Proteins with Detergent-and Nondetergent-based Method
Current Pharmaceutical Analysis·2023· 2 cited
page 1 of 6Next →

Frequent Co-authors

Tingjun Hou(28), Youyong Li(24), Huiyong Sun(17), Dan Li(12), Peichen Pan(11), Lei Xu(10), Huanqiu Li(8), Junmei Wang(7), Xuechu Zhen(6), Xiaohu Zhang(6), Haikuo Ma(5), Qinghua Hu(5), Mingyun Shen(4), Xiaojie Xu(4), Sudan He(4), Xiaotian Kong(4), Dan Li(3), Zhanhui Li(3), Xianwei Gui(3), Hansen Wang(3)