Patrick Garidel

Boehringer Ingelheim (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index9.4kcitations227works3.12yr avg
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Research Topics

Protein purification and stability(99), Lipid Membrane Structure and Behavior(44), Monoclonal and Polyclonal Antibodies Research(41), Viral Infectious Diseases and Gene Expression in Insects(36), Immune Response and Inflammation(32)

Publications227 total

Specific polysorbate fingerprints of CHO hydrolases and implications for indirect assays
Journal of Pharmaceutical Sciences·2025
Predicting the Dynamic Viscosity of High-Concentration Antibody Solutions with a Chemically Specific Coarse-Grained Model
The Journal of Physical Chemistry Letters·2025
Extraction of the polysorbate 20 and 80 fingerprint via generative modeling
International Journal of Pharmaceutics X·2025Open Access
Stabilisation of a monoclonal antibody formulation in the presence of poloxamer 188 and related PEG/PPG systems
Journal of Drug Delivery Science and Technology·2025Open Access
Predicting the Dynamic Viscosity of High-Concentration Antibody Solutions with a Chemically Specific Coarse-Grained Model
2025Open Access
Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling
European Journal of Pharmaceutics and Biopharmaceutics·2025
Fatty acid solubility determination in biopharmaceutical formulations containing polysorbate 20 using a design of experiments approach
Journal of Drug Delivery Science and Technology·2025
Competitive adsorption of a monoclonal antibody and amphiphilic polymers to the air–water interface
European Biophysics Journal·2025· 2 citedOpen Access
Anomalous Clouding Behavior of Polysorbate 80─Deciphering the Role of Nonesterified Components
Molecular Pharmaceutics·2025· 1 citedOpen Access
Proceedings of the 15 <sup>th</sup> European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals
mAbs·2025· 3 citedOpen Access
Optimized Protein–Excipient Interactions in the Martini 3 Force Field
Journal of Chemical Information and Modeling·2025· 3 cited
Interfacial and self-association behaviour of poloxamer 188 in aqueous solutions
Journal of Molecular Liquids·2025· 7 citedOpen Access
Micellar Solvent Accessibility of Esterified Polyoxyethylene Chains as Crucial Element of Polysorbate Oxidation: A Density Functional Theory, Molecular Dynamics Simulation and Liquid Chromatography/Mass Spectrometry Investigation
Molecular Pharmaceutics·2025· 3 citedOpen Access
Impact of vial quality on interactions, particle formation, container closure integrity, and gas permeability for frozen drug product storage
European Journal of Pharmaceutical Sciences·2025· 1 citedOpen Access
Polysorbates degrading enzymes in biotherapeutics – a current status and future perspectives
Frontiers in Bioengineering and Biotechnology·2025· 10 citedOpen Access
Optimized Protein–Excipient Interactions in the Martini 3 Force Field
2024Open Access
Residue-resolved insights into the stabilization of therapeutic proteins by excipients: A case study of two monoclonal antibodies with arginine and glutamate
mAbs·2024· 5 citedOpen Access
Evaluating the influence of the initial high molecular weight level on monoclonal antibody particle formation kinetics using a short-term chemical stress study
European Journal of Pharmaceutical Sciences·2024· 2 citedOpen Access
Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface
2024· 1 citedOpen Access
Comprehensive investigation of factors influencing the degradation of polysorbate 20: Insights into mechanisms and interactions using a design of experiments approach
Journal of Drug Delivery Science and Technology·2024· 1 citedOpen Access
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Frequent Co-authors

Klaus Brandenburg(14), Alfred Blume(14), Jörg Andrä(7), Michel H. J. Koch(7), Jörg Howe(6), Karl Lohner(5), Stefan Bassarab(4), Annegret Hildebrand(4), Thomas Gutsmann(4), Walter Richter(3), Michaela Blech(3), Karoline Bechtold-Peters(3), Guillermo Martínez de Tejada(3), Lena Heinbockel(3), Klaus Wuchner(3), Frank Steiniger(2), Manfred Roessle(2), Marcus Kostka(2), Karin M. Danzer(2), Udo Heinzelmann(2)