Michaela Blech

Boehringer Ingelheim (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.4kcitations56works2.42yr avg
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Research Topics

Protein purification and stability(43), Monoclonal and Polyclonal Antibodies Research(33), Viral Infectious Diseases and Gene Expression in Insects(16), Glycosylation and Glycoproteins Research(8), Protein Structure and Dynamics(7)

Publications56 total

Predicting the Dynamic Viscosity of High-Concentration Antibody Solutions with a Chemically Specific Coarse-Grained Model
The Journal of Physical Chemistry Letters·2025
Predicting the Dynamic Viscosity of High-Concentration Antibody Solutions with a Chemically Specific Coarse-Grained Model
2025Open Access
Competitive adsorption of a monoclonal antibody and amphiphilic polymers to the air–water interface
European Biophysics Journal·2025· 2 citedOpen Access
Spotlight on Glycan Pairing: The Generation and Impact of Monoclonal Antibody Asymmetrical Fc N-Glycan Pairs on Fc Receptor Interaction
ACS Pharmacology & Translational Science·2025Open Access
Optimized Protein–Excipient Interactions in the Martini 3 Force Field
Journal of Chemical Information and Modeling·2025· 3 cited
Optimized Protein–Excipient Interactions in the Martini 3 Force Field
2024Open Access
Residue-resolved insights into the stabilization of therapeutic proteins by excipients: A case study of two monoclonal antibodies with arginine and glutamate
mAbs·2024· 5 citedOpen Access
Evaluating the influence of the initial high molecular weight level on monoclonal antibody particle formation kinetics using a short-term chemical stress study
European Journal of Pharmaceutical Sciences·2024· 2 citedOpen Access
Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface
2024· 1 citedOpen Access
Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing
mAbs·2024· 5 citedOpen Access
Comprehensive analysis and characterization of glycan pairing in therapeutic antibodies and Fc-containing biotherapeutics: Addressing current limitations and implications for N-glycan impact
European Journal of Pharmaceutics and Biopharmaceutics·2024· 4 citedOpen Access
Challenges at Submicron Particle Characterisation: A Case Study Using Nanoparticle Tracking Analysis (NTA)
Journal of Pharmaceutical Innovation·2024· 3 cited
Exploring molecular determinants and pharmacokinetic properties of IgG1-scFv bispecific antibodies
mAbs·2024· 4 citedOpen Access
Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals
Journal of Pharmaceutical Innovation·2024· 4 cited
Viscosity Prediction of High-Concentration Antibody Solutions with Atomistic Simulations
Journal of Chemical Information and Modeling·2023· 29 citedOpen Access
Viscosity Prediction of High-Concentration Antibody Solutions with Atomistic Simulations
2023· 2 citedOpen Access
Backgrounded Membrane Imaging—A Valuable Alternative for Particle Detection of Biotherapeutics?
Journal of Pharmaceutical Innovation·2023· 8 cited
Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview
Pharmaceutics·2023· 47 citedOpen Access
Micro-flow imaging multi-instrument evaluation for sub-visible particle detection
European Journal of Pharmaceutics and Biopharmaceutics·2023· 10 cited
Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration
International Journal of Pharmaceutics X·2022· 12 citedOpen Access
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Frequent Co-authors

Patrick Garidel(38), Dariush Hinderberger(10), Lars V. Schäfer(9), Anne R. Karow‐Zwick(6), Tobias M. Prass(6), Daniel Seeliger(5), Sebastian Kube(5), Joey Studts(4), Julia Buske(4), Udo Bakowsky(4), Joschka Bauer(4), Fabian Higel(4), Alexander Kühn(3), W. Kaiser(3), Josef Hartl(3), Michael Strebl(3), Julia Baumeister(3), Maximilian Meudt(3), Sybille Ebert(3), Frank Rosenau(3)