Joschka Bauer

Boehringer Ingelheim (Germany) — Germany

Materials Science · Physical Sciences

11h-index263citations31works2.72yr avg
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Research Topics

Crystallization and Solubility Studies(13), X-ray Diffraction in Crystallography(13), Monoclonal and Polyclonal Antibodies Research(9), Protein purification and stability(7), Crystallography and molecular interactions(6)

Publications31 total

Bacterial Glutamine Synthetases as a Novel Metabolic Selection Marker to Improve CHO Cell Culture Performance Through Selection Stringency Modulation
Biotechnology Journal·2025· 1 citedOpen Access
Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based <i>in silico</i> approaches
mAbs·2024· 7 citedOpen Access
Biopharmaceutical Informatics: A Strategic Vision for Discovering Developable Biotherapeutic Drug Candidates
2024
How can we discover developable antibody-based biotherapeutics?
Frontiers in Molecular Biosciences·2023· 23 citedOpen Access
Embedding Dynamics in Intrinsic Physicochemical Profiles of Market-Stage Antibody-Based Biotherapeutics
Molecular Pharmaceutics·2022· 16 citedOpen Access
Embedding Dynamics in Intrinsic Physicochemical Profiles of Market-Stage Antibody-based Biotherapeutics
Figshare·2022Open Access
Stress-dependent Flexibility of a Full-length Human Monoclonal Antibody: Insights from Molecular Dynamics to Support Biopharmaceutical Development
Journal of Pharmaceutical Sciences·2021· 11 cited
Biotechnology and Bioengineering: Volume 118, Number 8, August 2021
Biotechnology and Bioengineering·2021Open Access
Modeling the impact of amino acid substitution in a monoclonal antibody on cation exchange chromatography
Biotechnology and Bioengineering·2021· 19 citedOpen Access
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
mAbs·2020· 21 citedOpen Access
Adaption of human antibody λ and κ light chain architectures to CDR repertoires
Protein Engineering Design and Selection·2019· 21 citedOpen Access
Universal nanothin silk coatings <i>via</i> controlled spidroin self-assembly
Biomaterials Science·2018· 25 citedOpen Access
Dimerization of the Conserved N-Terminal Domain of a Spider Silk Protein Controls the Self-Assembly of the Repetitive Core Domain
Biomacromolecules·2017· 27 cited
Conformational Stability and Interplay of Helical N- and C-Terminal Domains with Implications on Major Ampullate Spidroin Assembly
Biomacromolecules·2017· 30 cited
Die Schwarze Witwe und ihre Künste
2016
Acidic Residues Control the Dimerization of the N-terminal Domain of Black Widow Spiders’ Major Ampullate Spidroin 1
Scientific Reports·2016· 36 citedOpen Access
Resonance assignment of an engineered amino-terminal domain of a major ampullate spider silk with neutralized charge cluster
Biomolecular NMR Assignments·2016· 2 cited
Perfluorocarbon-filled poly(lactide-co-gylcolide) nano- and microcapsules as artificial oxygen carriers for blood substitutes: a physico-chemical assessment
Journal of Microencapsulation·2010· 24 cited
CCDC 247759: Experimental Crystal Structure Determination
The Cambridge Structural Database·2005Open Access
CCDC 211794: Experimental Crystal Structure Determination
The Cambridge Structural Database·2004Open Access
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Frequent Co-authors

Thomas Scheibel(6), Anne R. Karow‐Zwick(6), Sandeep Kumar(4), Michaela Blech(4), Giuseppe Licari(4), M.J. Goldcamp(4), M.J. Baldwin(4), C.L. Homrighausen(4), John Alexander(4), Sebastian Kube(3), S.E. Edison(3), L.N. Squires(3), D.T. Rosa(3), N.K. Vowels(3), N.L. Coker(3), Daniel Schaal(2), Kristian Schweimer(2), Stephan Schwarzinger(2), Pankaj Gupta(2), Sven Mathias(2)