Hans S.L.M. Nottet

Utrecht University — Netherlands

Immunology and Microbiology · Life Sciences

32h-index6.7kcitations63works0.02yr avg
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Research Topics

HIV Research and Treatment(48), Neuroinflammation and Neurodegeneration Mechanisms(27), Alzheimer's disease research and treatments(19), Immune Cell Function and Interaction(11), HIV/AIDS drug development and treatment(10)

Publications63 total

HIV-1 Can Persist in Aged Memory CD4+ T Lymphocytes With Minimal Signs of Evolution After 8.3 Years of Effective Highly Active Antiretroviral Therapy
JAIDS Journal of Acquired Immune Deficiency Syndromes·2009· 28 cited
Brain-derived human immunodeficiency virus-1 Tat exerts differential effects on LTR transactivation and neuroimmune activation
Journal of NeuroVirology·2007· 26 cited
Role of the pro‐inflammatory cytokines TNF‐α and IL‐1β in HIV‐associated dementia
European Journal of Clinical Investigation·2006· 264 cited
Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)
International Journal of Antimicrobial Agents·2005· 2 citedOpen Access
The blood–brain barrier: monocyte and viral entry into the brain
2005· 6 cited
Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin
Antiviral Research·2004· 5 cited
Multiple effects of HIV‐1 <i>trans</i>‐activator protein on the pathogenesis of HIV‐1 infection
European Journal of Clinical Investigation·2004· 99 cited
Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication
Antiviral Research·2003· 17 cited
Interactions of human immunodeficiency virus‐1 proteins with neurons: possible role in the development of human immunodeficiency virus‐1‐associated dementia
European Journal of Clinical Investigation·2002· 60 cited
Amyloid-β-induced chemokine production in primary human macrophages and astrocytes
Journal of Neuroimmunology·2002· 152 cited
Secretases as targets for drug design in Alzheimer’s disease
European Journal of Clinical Investigation·2002· 17 cited
The chemotherapeutic agent bleomycin in a two-drug combination with zidovudine, ritonavir or indinavir synergistically inhibits HIV Type-1 replication in peripheral blood lymphocytes
International Journal of Antimicrobial Agents·2001· 5 cited
Interactions between major histocompatibility complex class II surface expression and HIV: implications for pathogenesis
European Journal of Clinical Investigation·2001· 10 citedOpen Access
Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants
Trends in Neurosciences·2001· 186 cited
Activation of Human Macrophages by Amyloid-β Is Attenuated by Astrocytes
The Journal of Immunology·2001· 46 citedOpen Access
Enhanced expression of fractalkine in HIV-1 associated dementia
Journal of Neuroimmunology·2001· 80 cited
Intracellular pathways involved in TNF-α and superoxide anion release by Aβ(1–42)-stimulated primary human macrophages
Journal of Neuroimmunology·2001· 19 cited
Anti-HIV effect of iron chelators: different mechanisms involved
Journal of Clinical Virology·2001· 57 cited
The effect of deoxynucleosides on cell proliferation of peripheral blood lymphocytes treated with deferoxamine or hydroxyurea
Transfusion Science·2000
Macrophage inflammatory protein-1<i>α</i>(MIP-1<i>α</i>), MIP-1<i>β</i>, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions
Clinical & Experimental Immunology·2000· 106 citedOpen Access
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Frequent Co-authors

J. Verhoef(21), Howard E. Gendelman(10), Leonie A. Boven(10), Nanda Vos(10), Jeena Middel(7), Maarten R. Visser(6), Tjomme van der Bruggen(6), Loek de Graaf(6), Hessel A. Smits(5), B. Sweder van Asbeck(5), C R Flanagan(4), Joannes J.M. Marx(4), Cândida F. Pereira(4), Michael Bukrinsky(3), Stuart A. Lipton(3), Harris A. Gelbard(3), Marti Jett(3), P Genis(3), H. Snippe(3), Niki Georgiou(3)