Niels J. F. van den Broek

Janssen (Netherlands) — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index3.6kcitations36works0.02yr avg
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Research Topics

Signaling Pathways in Disease(9), FOXO transcription factor regulation(8), Peptidase Inhibition and Analysis(6), Cancer Mechanisms and Therapy(5), Amino Acid Enzymes and Metabolism(4)

Publications36 total

Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
PLoS Pathogens·2023· 10 citedOpen Access
Supplementary Figures 1-5 from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Data from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Supplementary Figures 1-5 from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Data from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Supplementary Table 1 from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Supplementary Table 1 from The Peptidyl-Isomerase Pin1 Regulates p27<sup>kip1</sup> Expression through Inhibition of Forkhead Box O Tumor Suppressors
2023Open Access
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
2022· 1 citedOpen Access
Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer
iScience·2022· 7 citedOpen Access
Multi-Omics Analysis Identifies Local N-Acetyl Aspartate Accumulation as a Feature of Castration Resistant Prostate Cancer
SSRN Electronic Journal·2021Open Access
Calibrating the Bacterial Growth Rate Speedometer: A Re-evaluation of the Relationship Between Basal ppGpp, Growth, and RNA Synthesis in Escherichia coli
Frontiers in Microbiology·2020· 25 citedOpen Access
Posttranslational Control of PlsB Is Sufficient To Coordinate Membrane Synthesis with Growth in Escherichia coli
mBio·2020· 34 citedOpen Access
Metabolic engineering of a carbapenem antibiotic synthesis pathway in Escherichia coli
Nature Chemical Biology·2018· 36 cited
Erratum: Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation
Nature·2017· 10 citedOpen Access
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
Nature·2017· 598 cited
F2-isoprostanes are formed from peroxidation of arachidonic acid.
Figshare·2015Open Access
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
Nature Cell Biology·2015· 277 citedOpen Access
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling
Oncogene·2015· 59 citedOpen Access
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Cancer Cell·2015· 796 citedOpen Access
Analysis of Cell Metabolism Using LC-MS and Isotope Tracers
Methods in enzymology on CD-ROM/Methods in enzymology·2015· 198 cited
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Frequent Co-authors

Arjan B. Brenkman(23), Peter L.J. de Keizer(12), Boudewijn Burgering(12), Petra van der Groep(7), Armando van der Horst(7), Alida M.M. Smits(7), Gillian Mackay(6), Christiaan F. Labuschagne(5), P. J. van Diest(5), Karen Blyth(4), Flore Kruiswijk(4), Ruud Berger(4), Eyal Gottlieb(3), Oliver D.K. Maddocks(3), Karen H. Vousden(3), Klaas W. Mulder(3), Marek Noga(3), Gregory Bokinsky(3), Gabriela Kalna(2), Vinay Bulusu(2)