Marina A. Lynch

Trinity College Dublin — Ireland

Neuroscience · Life Sciences

81h-index22.4kcitations282works6.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(125), Neuroscience and Neuropharmacology Research(103), Immune Response and Inflammation(42), Alzheimer's disease research and treatments(37), Tryptophan and brain disorders(33)

Publications282 total

Neuropharmacology - VSI: Microglia (Editorial)
Neuropharmacology·2025
Neonatal infection with Bordetella pertussis promotes autism-like phenotypes in mice
iScience·2024· 4 citedOpen Access
A case for seeking sex-specific treatments in Alzheimer’s disease
Frontiers in Aging Neuroscience·2024· 14 citedOpen Access
Acute Stress, Induced by IFNγ  + Aβ, and Chronic Stress, Induced by Age, Affect Microglia in a Sex-Specific Manner
Molecular Neurobiology·2023· 1 citedOpen Access
Microglia states and nomenclature: A field at its crossroads
Neuron·2022· 1.7k citedOpen Access
Sex-Related Microglial Perturbation Is Related to Mitochondrial Changes in a Model of Alzheimer’s Disease
Frontiers in Cellular Neuroscience·2022· 15 citedOpen Access
Exploring Sex-Related Differences in Microglia May Be a Game-Changer in Precision Medicine
Frontiers in Aging Neuroscience·2022· 131 citedOpen Access
The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific
Cells·2022· 17 citedOpen Access
Defining Microglial States and Nomenclature: A Roadmap to 2030
SSRN Electronic Journal·2022· 32 citedOpen Access
Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease
Communications Biology·2021· 164 citedOpen Access
Exercise-induced re-programming of age-related metabolic changes in microglia is accompanied by a reduction in senescent cells
Brain Behavior and Immunity·2020· 89 citedOpen Access
The role of the immune system in driving neuroinflammation
Brain and Neuroscience Advances·2020· 66 citedOpen Access
Can the emerging field of immunometabolism provide insights into neuroinflammation?
Progress in Neurobiology·2019· 87 cited
Explant of aortic stent grafts following endovascular aneurysm repair
Vascular·2019· 4 cited
The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages
Scientific Reports·2019· 150 citedOpen Access
Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice
Brain Pathology·2019· 192 citedOpen Access
Monocytes exposed to plasma from patients with Alzheimer’s disease undergo metabolic reprogramming
Neuroscience Research·2019· 6 citedOpen Access
Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid
Journal of Neuroinflammation·2018· 106 citedOpen Access
Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice
Mechanisms of Ageing and Development·2018· 23 cited
A shift to glycolysis accompanies the inflammatory changes in PBMCs from individuals with an IQ-discrepant memory
Journal of Neuroimmunology·2018· 4 cited
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Frequent Co-authors

Kingston H. G. Mills(7), Yvonne M. Nolan(7), Emily Vereker(5), M.L. Er̀rington(4), T.V.P. Bliss(4), Ciara Murray(4), Anthony Lyons(4), Aileen Lynch(4), Ana Rubio‐Araiz(3), Orla M. Finucane(3), Luke O'neill(3), Róisín M. McManus(3), Eric J. Downer(3), Virginia Mela(3), Darren S.D. Martin(3), Rachael M. Clarke(3), Aedín M. Minogue(3), Aine Marie Kelly(3), Veronica A. Campbell(3), Marco Colonna(2)