Rongshi Li

University of Nebraska Medical Center — United States

Chemistry · Physical Sciences

25h-index2.8kcitations61works5.02yr avg
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Research Topics

Synthesis and biological activity(8), Computational Drug Discovery Methods(7), Asymmetric Synthesis and Catalysis(6), Microbial Natural Products and Biosynthesis(5), Chemical Synthesis and Analysis(5)

Publications61 total

Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma
Journal of Experimental & Clinical Cancer Research·2024· 5 citedOpen Access
Analogs of Marinopyrrole A Show Enhancement to Observed <i>In Vitro</i> Potency against Acute Toxoplasma gondii Infection
Antimicrobial Agents and Chemotherapy·2021· 10 citedOpen Access
Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method
Molecules·2020· 12 citedOpen Access
Drugs for the Treatment of Zika Virus Infection
Journal of Medicinal Chemistry·2019· 100 citedOpen Access
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus
BMC Cancer·2019· 13 citedOpen Access
Enamine Catalytic Annulation of Azonaphthalenes: An Access to Indole Derivatives
Organic Letters·2019· 15 cited
Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters
Organic Letters·2019· 102 cited
Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy
Journal of Medicinal Chemistry·2018· 130 citedOpen Access
Abstract A16: The in vitro and in vivo activity of the pyrrolomycin marinopyrrole RL71 alone and combined with temsirolimus (TEM) in MYCN-amplified neuroblastoma (NB)
Cancer Research·2018
Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus
Antimicrobial Agents and Chemotherapy·2018· 32 citedOpen Access
Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus
2018· 4 citedOpen Access
Structure-guided and natural product-derived small molecules as antibiotic and anticancer agents
Journal of Regenerative Medicine·2018
Unique drug discoveries based on marinopyrrole and novel derivatives
Journal of Pharmacognosy & Natural Products·2016
Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine–G-Protein-Coupled-Receptor Interface
Journal of Medicinal Chemistry·2016· 31 citedOpen Access
Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway
Current Topics in Medicinal Chemistry·2016· 46 cited
Natural Product‐Based Drug Discovery
Medicinal Research Reviews·2015· 21 citedOpen Access
Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential
Journal of Medicinal Chemistry·2015· 367 citedOpen Access
Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products
Medicinal Research Reviews·2015· 30 cited
Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors
European Journal of Medicinal Chemistry·2014· 27 citedOpen Access
Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine
Journal of Medicinal Chemistry·2014· 25 cited
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Frequent Co-authors

Jerry Li(10), George L. Kenyon(6), Chunwei Cheng(6), Yong Qin(6), Saı̈d M. Sebti(5), Yan Liu(5), Jean Bernatchez(4), Hao Song(4), Alexander Chucholowski(4), Xiaowu Chen(3), Eugene A. Davidson(3), Stephan W. Morris(3), Jair L. Siqueira-Neto(3), Lili Pan(3), Tong Zhu(3), Zheng Yan(3), Thomas R. Webb(3), Zunhua Yang(3), Emmanuel W. Smith(3), Francis C. Peterson(3)