Emmanuel W. Smith

Medicine · Health Sciences

11h-index382citations16works0.02yr avg
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Research Topics

Chemokine receptors and signaling(4), Bacterial Genetics and Biotechnology(2), Antibiotic Resistance in Bacteria(2), HER2/EGFR in Cancer Research(2), Cell Adhesion Molecules Research(2)

Publications16 total

Human alpha-catenin monomer
EMPIAR dataset·2023Open Access
HMP1/alpha-catenin monomer
EMPIAR dataset·2023Open Access
Human dimeric alpha-catenin binding to F-actin
EMPIAR dataset·2023Open Access
HMP1/alpha-catenin binding with actin filaments
EMPIAR dataset·2023Open Access
Insights into POT1 structural dynamics revealed by cryo-EM
PLoS ONE·2022· 13 citedOpen Access
Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography
Scientific Reports·2019· 31 citedOpen Access
Incentives and social relationships of hunters and traders in a Liberian bushmeat system
Biological Conservation·2019· 16 citedOpen Access
Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site
Biochemistry·2016· 11 citedOpen Access
Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine–G-Protein-Coupled-Receptor Interface
Journal of Medicinal Chemistry·2016· 31 citedOpen Access
Structures of <i>Pseudomonas aeruginosa</i> LpxA Reveal the Basis for Its Substrate Selectivity
Biochemistry·2015· 24 citedOpen Access
Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography
Journal of the American Chemical Society·2015· 95 citedOpen Access
Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine
Journal of Medicinal Chemistry·2014· 25 cited
Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-binding Motif
Journal of Biological Chemistry·2014· 52 citedOpen Access
Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model
International Journal of Oncology·2013· 25 citedOpen Access
Fragment-Based Optimization of Small Molecule CXCL12 Inhibitors for Antagonizing the CXCL12/CXCR4 Interaction
Current Topics in Medicinal Chemistry·2013· 21 citedOpen Access
Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A β-Lactamase
Journal of Medicinal Chemistry·2012· 38 cited

Frequent Co-authors

Yu Chen(7), Brian F. Volkman(4), Rangarajan ES(4), Tina Izard(4), Yan Liu(3), Francis C. Peterson(3), Rongshi Li(3), Derek A. Nichols(2), Priyadarshini Jaishankar(2), Adam R. Renslo(2), Yu Chen(2), Anthony E. Getschman(2), Kyle G. Kroeck(2), Frederick Cohen(2), Logan D. Andrews(2), Joshua J. Ziarek(2), Jacqueline C. Hargis(1), Ruslan Sanishvili(1), Kyle DeFrees(1), Kenneth K. Wang(1)